2243-69-8Relevant articles and documents
Broyles,Easley
, p. 2233,2234 (1960)
Mizoroki-heck reactions with 4-phenoldiazonium salts
Schmidt, Bernd,Hoelter, Frank,Berger, Rene,Jessel, Soenke
supporting information; experimental part, p. 2463 - 2473 (2010/12/25)
Significantly better yields were achieved in Mizoroki-Heck reactions using 4-phenoldiazonium salts instead of their O-alkylated analogues under otherwise identical conditions. We found that a one-flask deacetylation-diazotation- precipitation sequence starting from paracetamol or acetanilides derived thereof provides a convenient access to the required diazonium tetrafluoroborates. The utility of these arylating agents in palladium-catalyzed C-C bond forming reactions was demonstrated for a one-flask-synthesis of the heterocyclic core of the drug aripiprazole. Notably, the diazonium salt formation from an acetanilide could be combined with two Pd-catalyzed steps in a one-flask sequence, without any exchange of solvents or isolation of intermediates.
Vinylsilylalkoxy arylbenzotriazole compounds and UV absorbing compositions made therefrom
-
, (2008/06/13)
Vinylsilylalkoxy arylbenzotriazol monomers such as 2-[3′-t-butyl-5′-(3″-dimethylvinylsilylpropoxy)-2′-hydroxy-phenyl]-5-methoxybenzotriazole are disclosed. These monomers can be incorporated in optically clear silicone polymers to form intraocular lenses, contact lenses, and the like, which have UV absorbing properties.
