7475-63-0 Usage
Uses
Used in Illicit Drug Formulations:
1-(1-methyl-4-phenylpiperidin-4-yl)propan-1-one is used as a psychoactive substance in the illicit drug market for its stimulant and entactogenic effects. It is often found in designer drugs, which are created to mimic the effects of controlled substances.
Used in Research and Forensic Analysis:
In a controlled and legal context, 1-(1-methyl-4-phenylpiperidin-4-yl)propan-1-one may be used as a research compound to study its effects on the central nervous system and to develop potential treatments for addiction or other related conditions. Additionally, it can be utilized in forensic analysis to identify and track the presence of this substance in cases of drug-related crimes or health incidents.
Check Digit Verification of cas no
The CAS Registry Mumber 7475-63-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,4,7 and 5 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 7475-63:
(6*7)+(5*4)+(4*7)+(3*5)+(2*6)+(1*3)=120
120 % 10 = 0
So 7475-63-0 is a valid CAS Registry Number.
7475-63-0Relevant academic research and scientific papers
Opioids and efflux transporters. Part 3: P-glycoprotein substrate activity of 3-hydroxyl addition to meperidine analogs
Mercer, Susan L.,Cunningham, Christopher W.,Eddington, Natalie D.,Coop, Andrew
experimental part, p. 3638 - 3640 (2009/04/11)
Numerous studies have shown that many clinically employed opioid analgesics are substrates for P-glycoprotein (P-gp), suggesting that up-regulation of P-gp may contribute to the development of central tolerance to opioids. The studies herein focus on the development of SAR for P-gp substrate activity in the meperidine series of opioids. Addition of a 3-OH to meperidine and the ketone analog of meperidine yielding bemidone and ketobemidone, respectively, significantly increased P-gp substrate affinity. The results of this study have implications in the development of novel analgesics to be utilized as tools to study the contribution of P-gp on the development of central tolerance to opioids.
