7477-67-0

Usage

Uses

Used in Chemical Analysis:
Bispyrazolone is used as a reagent for the detection and determination of cyanide, a highly toxic compound. Its ability to react with cyanide allows for accurate measurement and analysis of cyanide levels in various samples.
Used in Food Processing:
In the food processing industry, Bispyrazolone is used in an experimental procedure to remove linamarin, a cyanogenic glycoside found in starch from cassava roots. This is achieved by using plant cell wall-degrading enzymes, xylanase and cellulase, which break down the cyanogenic compounds and improve the safety and quality of the cassava-derived products.
Used in Medical Diagnostics:
Bispyrazolone is used for the spectrophotometric determination and quantization of urea in urine samples. This method allows for the accurate measurement of urea levels, which can be an important indicator of kidney function and overall health.
Used in Environmental Analysis:
Bispyrazolone is also used in the assay of cyanogenic compounds and the determination of ammonia in environmental samples. This helps in monitoring and controlling the levels of these potentially harmful substances in the environment, ensuring safety and sustainability.

Upstream product

• 4719-41-9 4-Diethylamino-2-methyl-phenylimino-3-methyl-1-phenyl-2-pyrazolin-5-on 
• 89-25-8 edaravone 
• 104525-76-0 4-<-4--2-methylphenylimino>-3-methyl-1-phenyl-2-pyrazolin-5-on 
• 7446-08-4 selenium(IV) oxide 
• 19735-89-8 3-methyl-1-phenylpyrazolin-5(4H)-one 
• 64-17-5 ethanol 
• 98-95-3 nitrobenzene 
• 87085-88-9 5-Methyl-4-nitroso-2-phenyl-2H-pyrazol-3-ol 
• 4719-52-2 4-<phenylimino>-3-methyl-1-phenyl-2-pyrazolin-5-on 
• 117985-07-6 4-Diethylamino-phenylimino-3-methyl-1-phenyl-2-pyrazolin-5-on 
• 41927-23-5 4-bromo-3-methyl-1-phenylpyrazol-5-one 

Downstream Products

• 143099-92-7 3-(1-formyl-2-dimethylaminoethenyl)-4-methyl-1,6-diphenyl-furo<2,3-c:5,4-c'>dipyrazole 
• 143099-91-6 4-<5-chloro-3-(1-formyl-2-dimethylaminoethenyl)-1-phenyl-1H-pyrazol-4-yl>-2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one 
• 6334-24-3 5,5'-dimethyl-2,2'-diphenyl-2H,2'H-[4,4']bipyrazolylidene-3,3'-dione 
• 143099-93-8 4-(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)-2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one 
• 143100-01-0 (Z)-2-(4-Methyl-1,6-diphenyl-1,6-dihydro-furo[2,3-c;5,4-c']dipyrazol-3-yl)-3-{4-[(Z)-2-(4-methyl-1,6-diphenyl-1,6-dihydro-furo[2,3-c;5,4-c']dipyrazol-3-yl)-3-oxo-propenyl]-piperazin-1-yl}-propenal 
• 143099-96-1 3-(1-formyl-2-morpholinylethenyl)-4-methyl-1,6-diphenyl-furo<2,3-c:5,4-c'>dipyrazole 
• 143099-97-2 3-(1-formyl-2-piperazinylethenyl)-4-methyl-1,6-diphenyl-furo<2,3-c:5,4-c'>dipyrazole 
• 143099-95-0 3-(1-formyl-2-piperidinylethenyl)-4-methyl-1,6-diphenyl-furo<2,3-c:5,4-c'>dipyrazole 
• 143100-00-9 3-(1-phenyl-4-pyrazolyl)-4-methyl-1,6-diphenyl-furo<2,3-c:5,4-c'>dipyrazole 
• 143099-99-4 3-(4-pyrazolyl)-4-methyl-1,6-diphenyl-furo<2,3-c:5,4-c'>dipyrazole 
• 143099-98-3 3-(4-isoxazolyl)-4-methyl-1,6-diphenyl-furo<2,3-c:5,4-c'>dipyrazole 
• 124009-63-8 5,5''-dihydroxy-3,3'',5'-trimethyl-1,1'',2'-triphenyl-1H,1''H-[4,4':4',4''-terpyrazol]-3'(2'H)-one 

Relevant academic research and scientific papers

Preparation method of edaravone related substances

The invention belongs to the field of chemical medicines and particularly relates to a preparation method of an edaravone dimer and an edaravone trimer. The preparation method includes the steps of: adding edaravone to an organic solvent, adding a carbonate and performing a reaction under a high-pressure microwave condition to simultaneously produce the edaravone dimer and edaravone trimer. The preparation method is short in reaction time, employs environment-friendly solvent, has low damage on instrument, greatly reduces reaction time and saves time cost, can simultaneously produce the two edaravone related substances and improves utilization rate of raw materials.

Detection and Treatment of Schizophrenia

The present invention provides a method for diagnosing schizophrenia, and a schizophrenia diagnostic reagent or device for use in the method. The present invention further provides a therapeutic or ameliorating agent for schizophrenia, which is effective for the treatment or amelioration of schizophrenia. The therapeutic or ameliorating agent for schizophrenia contains a carbonyl scavenger or a carbonyl-modified protein formation inhibitor as an active ingredient. The method for diagnosing schizophrenia according to the present invention includes measuring at least one parameter in a subject, the parameter being selected from the group consisting of: (1) a genetic abnormality of glyoxalase I gene; (2) the expression level or activity of glyoxalase I in a biological sample; (3) the amount of a carbonyl compound or a carbonyl-modified protein that is a protein modified with the carbonyl compound; and (4) the amount of pyridoxal in a biological sample.

New synthesis of pyrazolo[3,4-b][1,4,5]benzothiadiazepine, -[1,4,5]benzoxadiazepine, -[1,4,5]benzotriazepine and pyrazolo[3,4-b]quinoxaline derivatives

New pyrazolo[3,4-b][1,4,5]benzothiadiazepine and its analogues 3 have been obtained by reaction of 4-nitrosopyrazoles 1 with 2-aminothiophenol 2a and its analogues 2b,c. Under fused conditions, dipyrazolyl derivatives 7a was obtained with a trace amount of quinoxaline 5a. On the other hand, 5b and 7b were obtained in equal amounts. A proposed pathway is presented.

Investigations on the Reaction of Pyrazolone Azomethine Dyes with 2-Pyrazolin-5-one-Derivatives

The reaction between pyrazolone azomethine dyes 1 and different 2-pyrazolin-5-ones 2 was investigated.Among the reaction products compounds 5 > was isolated, which hitherto was unknown as a product of this reaction.A new reaction pathway is proposed.

Investigation of Reactions of Pyrazolin-Azomethin Dyes with 2-Pyrazolin-5-one

The pyrazolin-azomethin dyes (3a-d) from 1-phenyl-3-methyl-2-pyrazolin-5-one and various photographic developers have been obtained.The reactions of decolourization of dyes during the 3-methyl-1-phenyl-2-pyrazolin-5-one action was investigated.We ascertained that the substituent changes in the developer had not only the influence on decolourization rate but they also had influence on the order change of the reaction.The various solvents had the same influence on the reaction rate of decolourization.

Process for preparing fiber-reactive phthalocyanine azo dyes

Process for preparing fiber-reactive water-soluble phthalocyanine azo dyes, using the following conversion stages STR1 followed by the diazonium coupling of the fiber-reactive group to the pyrazole ring. The novel intermediates are desirable products.

Process for preparing 2,5-dimethyl-3-(2H)-furanone

There is disclosed a simple, economical process for preparing 2,5-dimethyl-3-(2H)-furanone by hydrolysis of the dimer of diacetyl at a temperature of 20°C to 120°C and in the presence of an acid, mineral or organic, or of a cationic resin, with elimination of a acetic acid.