7477-77-2

Upstream product

• 21034-30-0 4-bromo-5,5-diphenyl-dihydro-furan-2-one 
• 7746-94-3 5,5-diphenyldihydrofuran-2(3H)-one 
• 201230-82-2 carbon monoxide 
• 3923-51-1 1,1-diphenylprop-2-en-1-ol 
• 606-84-8 3,3-diphenylacrylic acid 
• 65955-77-3 diphenylmethoxy propiolate 
• 108-24-7 acetic anhydride 
• 72081-07-3 diphenyl-5,5 dioxa-4,10 exo-tricyclo<5.2.1.0^2.6>decene-8 one-3 
• 112751-96-9 4-Benzenesulfonyl-5,5-diphenyl-dihydro-furan-2-one 
• 85704-21-8 hydroxy-2 diphenyl-5,5 dihydro-2,5 furanne 
• 79710-40-0 diphenylmethyl (D)propiolate 
• 109648-63-7 3-hydroxy-2-oxo-5,5-diphenyl-tetrahydro-furan-3-carboxylic acid 
• 530-48-3 1,1-Diphenylethylene 
• 6118-51-0 exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride 

Downstream Products

• 4452-11-3 1,2-diphenylprop-2-en-1-one 
• 6620-27-5 4,5-diphenylfuran-2(5H)-one 
• 7496-07-3 (5-oxo-2,2-diphenyl-tetrahydro-[3]furyl)-acetic acid 

Relevant academic research and scientific papers

Copper-catalyzed aerobic C-C bond cleavage of lactols with N-hydroxy phthalimide for synthesis of lactones

The transformation of cyclic hemiacetals (lactols) into lactones has been achieved by Cu-catalyzed aerobic C-C bond cleavage in the presence of N-hydroxy phthalimide (NHPI). The present process is composed of a multistep sequence including a) formation of exo-cyclic enol ethers by dehydration; b) addition of phthalimide N-oxyl radical to the enol ethers followed by trapping of the resulting C-radicals with molecular oxygen to form peroxy radicals; c) reductive generation of oxy radicals and subsequent β-radical fragmentation to generate lactones.

A New Route to 2(5H)-Furanones via Ruthenium-catalysed Oxidative Cyclocarbonylation of Allylic Alcohols

Several 2(5H)-furanoses are readily prepared in moderate to high yields by ruthenium-catalysed oxidative cyclocarbonylation of 1,1-disubstituted allyl alcohols.

METHYL 3-PHENYLSULPHONYL ORTHOPROPIONATE: AN EFFICIENT REAGENT FOR THE SYNTHESIS OF γ-LACTONES AND BUTENOLIDES

Treatment of methyl 3-phenylsulphonyl orthopropionate with n-BuLi gives the corresponding carbanion which reacts with aldehydes or ketones to yield β-phenylsulphonyl-γ-lactones.Base-catalysed elimination yields α,β or β,γ-butenolides.

Reaction of Olefins with Malonic Acid Derivatives in the Presence of Manganese(III) Acetate

The reaction of methylmalonic acid with mono- and disubstituted olefins in the presence of manganese(III) acetate yielded 2-carboxy-2-methyl-4-butanolides in moderate to good yields.The reactions of bromomalonic acid and chloromalonic acid with a variety

ETUDE DE L'ACTION DES ALKYLMAGNESIENS PRIMAIRES ET ARYLMAGNESIENS SUR LES ANHYDRIDES TRICYCLIQUES PONTES

The reaction of primary alkyl and aromatic Grignard reagents with bridged tricyclic dicarboxylic anhydrides gives the corresponding dialkylated tricyclic lactones via di-addition process.The lactones were transformed by retro-Diels-Alder reaction into 4,4-dialkylated butenolides.

REACTION DES ORGANOLITHIENS AVEC L'ETHOXY-5 DIHYDRO-2,5 FURANNONE-2. PREPARATION DE δ-2 BUTENOLIDES DISUBSTITUES SUR LE CARBONE-4.

Organolithium react with 5-ethoxy 2,5 dihydro-furan-2-one 1, easily obtained by photoxidation of furfural, leading selectively to 5-hydroxy-2,5-dihydro-furans 4 or to 5-ethoxy-2,5 dihydro-furans 5 disubstituted on carbon 4; the oxydation of the hemi-acetals 4 transforms them with good yields in Δ-2 butenolides disubstituted on carbon 4.

Lactones, I: Synthesis of Dihydroxylated Diphenylethanamines via &α-Amino-&γ-lactones

Treatment of α-amino-γ-lactones with phenyllithium yields the 2-amino-1,1-diphenylalkane-1,4-diols 2a-f which can be classified as dihydroxylated diphenylethanamines.

The Oxidation of 3,3-Diphenyl-2-propenoic Acid with Manganese(III) Acetate

The oxidation of 3,3-diphenyl-2-propenoic acid with manganese(III) acetate in boiling acetic gave 3,3-diphenyl-2-propenyl acetate, 4-acetoxymethyl-5,5-diphenyltetrahydro-2-furanone, 3,3-diphenyl-2-propenal, 5,5-diphenyl-2,5-dihydro-2-furanone, 4-acetoxy-5,5-diphenyltetrahydro-2-furanone, benzophenone, and 2-oxo-5,5-diphenyltetrahydro-4-furancarboxylic acid.The reaction pathways are discussed.

A FACILE AND GENERAL ROUTE TO 4-SUBSTITUTED-2 BUTENOLIDES

Grignar reagents react with 7-oxabicyclohept-5-ene-2,3-dicarboxylic anhydride and produce in high yields the corresponding substituted bicyclo-γ-butanolides.These lactones produce the title compounds by retro Diels-Alder reaction during distillation.