74819-50-4

Upstream product

• 73155-38-1 (6RS,7RS,9SR)-7-(1-hydroxyethyl)-8-oxo-3-oxa-1-azabicyclo<4.2.0>octane-2-spirocyclohexane 
• 4457-32-3 4-nitrobenzyl chloroformate 
• 73155-38-1 (6RS,7RS,9RS)-7-(1-hydroxyethyl)-8-oxo-3-oxa-1-azabicyclo<4.2.0>octane-2-spirocyclohexane 
• 106673-93-2 (6RS,9SR)-7-(1-hydroxyethyl)-8-oxo-7-(toluene-p-sulphenyl)-3-oxa-1-azabicyclo<4.2.0>octane-2-spirocyclohexane 
• 106673-89-6 7-acetyl-8-oxo-7-(toluene-p-sulphenyl)-3-oxa-1-azabicyclo<4.2.0>octane-2-spirocyclohexane 
• 106673-90-9 7-acetyl-7-methylthio-8-oxo-3-oxa-1-azabicyclo<4.2.0>octane-2-spirocyclohexane 
• 106673-92-1 7-acetyl-7-bromo-8-oxo-3-oxa-1-azabicyclo<4.2.0>octane-2-spirocyclohexane 
• 106687-68-7 (6RS,9SR)-7-(1-hydroxyethyl)-7-methylthio-8-oxo-3-oxa-1-azabicyclo<4.2.0>octane-2-spirocyclohexane 
• 73659-95-7 (6RS,7SR)-7-acetyl-8-oxo-3-oxa-1-aza-bicyclo[4.2.0]octane-2-spirocyclohexane 

Downstream Products

• 65991-26-6 (5RS,6RS,8RS)-p-nitrobenzyl 3-<2-(p-nitrobenzyloxycarbonylamino)ethylthio>-6-(1-p-nitrobenzyloxycarbonyloxyethyl)-7-oxo-1-azabicyclo<3.2.0>hept-2-ene-2-carboxylate 
• 133380-98-0 (5RS,6RS,8RS)-p-nitrobenzyl 3-diphenylthiophosphinoyl-6-(1-p-nitrobenzyloxycarbonyloxyethyl)-7-oxo-1-azabicyclo<3.2.0>hept-2-ene-2-carboxylate 
• 76347-45-0 p-nitrobenzyl (3RS,4RS)-4-<3-<(1RS)-1-p-nitrobenzyloxycarbonyloxyethyl>-2-oxoazetidin-4-yl>-3-oxobutanoate 
• 76335-78-9 (5RS,6RS,8RS)-p-nitrobenzyl 3,7-dioxo-6-(1-p-nitrobenzyloxycarbonyloxyethyl)-1-azabicyclo<3.2.0>heptane-2-carboxylate 
• 76335-76-7 <(3RS,4RS)-3-<(RS)-1-p-nitrobenzyloxycarbonyloxyethyl>-2-oxaazetidin-4-yl>acetic acid 
• 72690-84-7 (3RS,4RS)-4-(2-hydroxyethyl)-3-<(1RS)-1-p-nitrobenzyloxycarbonyloxyethyl>azetidin-2-one 
• 76335-76-7 (+/-)-4β-carboxymethyl-3β-<(1S^*)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>azetidin-2-one 
• 64066-69-9 Carbonic acid (R)-1-[(2S,3S)-2-(2-hydroxy-ethyl)-4-oxo-azetidin-3-yl]-ethyl ester 4-nitro-benzyl ester 

Relevant academic research and scientific papers

Olivanic Acid Analogues. Part 8. Halogenation and Sulphenylation Reactions leading Selectively to cis-Carbapenem Precursors; Stereospecific Synthesis of (+/-)-6-Epithienamycin

Introduction of halogen or sulphenyl substituents at C-7 of ketone 1, followed by stereospecific reduction steps, provides a selective route either to the (6RS,7RS,9RS) isomer 11 or to the (6RS,7RS,9SR) isomer 14 of 7-(1-hydroxyethyl)-8-oxo-3-oxa-1-azabic

Sulphenylation and Halogenation Reactions leading Selectively to cis-Carbapenem Precursors; Stereospecific Synthesis of (+/-)-6-Epithienamycin

Introduction of sulphenyl or halogen substituents at C-7 of ketone (1), followed by stereospecific reduction steps, provides a selective route either to the (6RS,7RS,9SR) or to the (6RS,7RS,9RS) isomers, (10) and (11), of 7-(1-hydroxyethyl)-8-oxo-1-aza-3-