74829-85-9Relevant academic research and scientific papers
Deaminative metal-free reaction of alkenylboronic acids, sodium metabisulfite and Katritzky salts
Zhu, Tonghao,Shen, Jia,Sun, Yuyuan,Wu, Jie
supporting information, p. 915 - 918 (2021/02/06)
A convenient and efficient approach to (E)-alkylsulfonyl olefinsviaa metal/light-free three-component reaction of alkenylboronic acids, sodium metabisulfite and Katritzky salts is described. This alkylsulfonylation proceeds smoothly with a broad substrate scope, leading to diverse (E)-alkylsulfonyl olefins in moderate to good yields. During the process, excellent functional group tolerance is observed and sodium metabisulfite is used as the source of sulfur dioxide. Mechanistic studies show that the alkyl radical generatedin situfrom Katritzky saltviaa single electron transfer with alkenylboronic acid or DIPEA is the key step for providing an alkyl radical intermediate, which undergoes further alkylsulfonylation with sulfur dioxide.
Vinyl sulfone synthesisviacopper-catalyzed three-component decarboxylative addition
An, Seunghwan,Lee, Sunwoo,Song, Kwang Ho
supporting information, p. 7827 - 7831 (2021/09/28)
The synthesis of vinyl sulfone derivativesviathe reaction of arylpropiolic acids, K2S2O5, and aryl boronic acids is reported. The CuBr2/1,10-phenanthroline catalytic system in the presence of acetic acid provide
