74863-35-7Relevant articles and documents
Epimerisation-free Peptide Formation from Carboxylic Acid Anhydrides and Azido Derivatives
Bosch, Imma,Urpi, Felix,Vilarrasa, Jaume
, p. 91 - 92 (2007/10/02)
Conversion of C-terminal carboxy groups of N-protected α-amino acids to the corresponding 3,5-dinitrobenzoyl mixed anhydrides, followed by treatment with α-azido esters and trialkylphosphines, affords good yields of peptides, without appreciable formation
NEW COUPLING REAGENTS IN PEPTIDE CHEMISTRY
Knorr, Reinhard,Trzeciak, Arnold,Bannwarth, Willi,Gillessen, Dieter
, p. 1927 - 1930 (2007/10/02)
2-(1H-Benzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate (HBTU) has been applied as coupling reagent to solid phase peptide synthesis.Furthermore, a general synthetic procedure for new derivatives of different N-hydroxy compounds has been developed.They either act as excellent activating reagents causing low racemization during condensation of peptide segments or are useful tools for the formation of active esters suitable for couplings in mixed aqueous / organic media, respectively.
Phenylalanylvalylarginine derivative, process for producing same and method for measuring activity of enzymes using same
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, (2008/06/13)
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