74863-35-7Relevant academic research and scientific papers
Epimerisation-free Peptide Formation from Carboxylic Acid Anhydrides and Azido Derivatives
Bosch, Imma,Urpi, Felix,Vilarrasa, Jaume
, p. 91 - 92 (2007/10/02)
Conversion of C-terminal carboxy groups of N-protected α-amino acids to the corresponding 3,5-dinitrobenzoyl mixed anhydrides, followed by treatment with α-azido esters and trialkylphosphines, affords good yields of peptides, without appreciable formation
A NEW CONVENIENT APPROACH TO PEPTIDE SYNTHESIS
Singh, Usha,Ghosh, Sunil K.,Chadha, Mohindra S.,Mamdapur, Vasant R.
, p. 255 - 258 (2007/10/02)
A new and highly efficient method based on a redox reaction using diphenyl diselenide and tributylphosphine for the general synthesis of peptides is described.The side reaction due to selenophenol formation is overcome by using chalcone as a scavenger or
NEW COUPLING REAGENTS IN PEPTIDE CHEMISTRY
Knorr, Reinhard,Trzeciak, Arnold,Bannwarth, Willi,Gillessen, Dieter
, p. 1927 - 1930 (2007/10/02)
2-(1H-Benzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate (HBTU) has been applied as coupling reagent to solid phase peptide synthesis.Furthermore, a general synthetic procedure for new derivatives of different N-hydroxy compounds has been developed.They either act as excellent activating reagents causing low racemization during condensation of peptide segments or are useful tools for the formation of active esters suitable for couplings in mixed aqueous / organic media, respectively.
Synthesis of Chiral Dipeptides by means of Asymmetric Hydrogenation of Dehydro Dipeptides
Ojima, Iwao,Kogure, Tetsuo,Yoda, Noriko,Suzuki, Tadashi,Yatabe, Momoko,Tanaka, Toshiyuki
, p. 1329 - 1334 (2007/10/02)
Asymmetric hydrogenation of various dehydro dipeptides was carried out by using rhodium complex catalysts with a variety of chiral diphosphine ligands.The efficiency of chiral diphosphine ligands as well as the effect of the chiral center in the substrate
