74959-56-1Relevant academic research and scientific papers
Synthesis of 2-amino-substituted-1,3,4-thiadiazoles via 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) mediated intramolecular C-S bond formation in thiosemicarbazones
Singh, Sarangthem Joychandra,Rajamanickam, Suresh,Gogoi, Anupal,Patel, Bhisma K.
supporting information, p. 1044 - 1047 (2016/02/18)
An effective oxidative intramolecular cyclization (C-S bond formation) of thiosemicarbazones using 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) has been developed to afford a diverse array of 2-amino-substituted-1,3,4-thiadiazoles. The attractive featu
FeCl3-promoted synthesis of 1,3,4-thiadiazoles under combined microwave and ultrasound irradiation in water
Feng, Huangdi,Ying, Xili,Peng, Yanqing,Van Der Eycken, Erik V.,Liu, Chuanduo,Zhao, Shanshan,Song, Gonghua
, p. 681 - 686 (2013/07/26)
An eco-friendly and efficient synthesis of substituted 1,3,4-thiadiazole derivatives has been developed. This aqueous heterogeneous approach proceeds smoothly and quickly under combined microwave and ultrasound irradiation in the presence of FeCl3.
Complexes of silicon and phosphorus chlorides with nitrogen-containing bases as the condensing agents in the synthesis of amides
Besgubenko, L. V.,Pipko, S. E.,Sinitsa, A. D.
, p. 1382 - 1390,9 (2020/09/16)
High effectiveness of new condensing agents on the basis of complexes of silicon and phosphorus chlorides with nitrogen-containing bases in the synthesis of amides from carboxylic acids and amines and also in heterocyclization is shown. Factors affecting the readiness of formation of the amide bond and the yields of the final products are established.
Dithiocarbamate as an efficient intermediate for the synthesis of 2-amino-1,3,4-thiadiazoles in water
Aryanasab, Fezzeh,Halimehjani, Azim Ziyaei,Saidi, Mohammad R.
supporting information; experimental part, p. 790 - 792 (2010/03/24)
A new and facile protocol for the synthesis of 2-amino-1,3,4-thiadiazoles in water is described. Reaction of acid hydrazides with easily prepared dithiocarbamates gives the corresponding thiadiazoles in moderate to excellent yields. 2-Amino-1,3,4-oxadiazoles were not observed as side products using this procedure.
