74975-25-0

Basic information

• Product Name: 4-benzoylpyridine-3-carboxylic acid
• CAS NO: 74975-25-0
• Molecular Formula: C₁₃H₉NO₃
• Molecular Weight: 227.2155
• Mol File: 74975-25-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 466.9°C at 760 mmHg
• Flash Point: 236.2°C
• Density: 1.311g/cm³
• Vapor Pressure: 1.61E-09mmHg at 25°C
• Refractive Index: 1.622
• CAS DataBase Reference: 4-benzoylpyridine-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-benzoylpyridine-3-carboxylic acid(74975-25-0)
• EPA Substance Registry System: 4-benzoylpyridine-3-carboxylic acid(74975-25-0)

Safety Data

• Hazardous Substances Data: 74975-25-0(Hazardous Substances Data)

Upstream product

• 24015-80-3 3-methyl-4-benzylpyridine 
• 4664-08-8 cinchomeronic anhydride 
• 71-43-2 benzene 
• 104084-46-0 4-[hydroxy(phenyl)methyl]-N,N-diisopropylnicotinamide 
• 77924-01-7 N,N-diisopropylnicotinamide 
• 88329-46-8 N,N-Diisopropyl-4-benzoyl-3-pyridinecarboxamide 
• 849322-39-0 1-phenyl-1,3-dihydrofuro[3,4-c]pyridin-3-one 
• 611-74-5 N,N-dimethylbenzamide 
• 20260-53-1 pyridine-3-carbonyl chloride hydrochloride 
• 16214-99-6 N-benzyl-3-methyl-pyridinium chloride 
• 100-44-7 benzyl chloride 

Downstream Products

• 14548-46-0 4-Benzoylpyridine 
• 46492-08-4 benz[g]isoquinoline-5,10-dione 
• 104867-63-2 3-chloro-3-phenyl-6-azaphthalide hydrochloride 
• 175857-58-6 N-diphenylphosphinoylmethyl-N-methyl-3-benzoyl-2-pyridinecarboxamide 
• 104867-65-4 2-benzyl-3-hydroxy-3-phenyl-6-azaindolinone 
• 104867-69-8 N-tert-butyl-4-benzoylnicotinamide 
• 849322-40-3 1-hydroxy-1-phenyl-1,2-dihydro-3H-pyrrolo[3,4-c]pyridin-3-one 
• 104867-64-3 1-Chloro-1-phenyl-1H-furo[3,4-c]pyridin-3-one 

Relevant articles and documents

Studies on the 4-benzoylpyridine-3-carboxamide entity as a fragment model of the Isoniazid-NAD adduct

An ortho-metallatkm-electrophilic substitution sequence was employed as a key step to build the 4-benzoylpyridine framework. It was found that 4-benzoylpyridine-3-carboxamide and an N-pyridyl alkylated derivative both exist in a unique cyclized hemiamidal

Heterocyclic compounds, their production and use as tachykinin reactor antagonists

A novel compound represented by the formula: STR1 wherein Ring A and Ring B respectively stands for an optionally substituted homo- or hetero-cyclic ring, and at least one of them stands for an optionally substituted heterocyclic ring stand; Ring C stands for an optionally substituted benzene ring; R stands for a hydrogen atom or an optionally substituted hydrocarbon residue; one of X and Y stands for --NR1 -- (R1 stands for a hydrogen atom or an optionally substituted hydrocarbon residue) or --O--, and the other stands for--CO-- or --CS--, or one of them stands for --N= and the other stands for =CR2 -- (R2 stands for a hydrogen atom, a halogen atom, an optionally substituted hydrocarbon residue, an optionally substituted amino group or an optionally substituted hydroxyl group); n denotes 1 or 2 or salts thereof which have an excellent tachykinin receptor antagonistic action and inhibitory action on plasma extravasation.

SYNTHESIS OF 2-AZAANTRAQUINONE AND ITS DERIVATIVES

The acylation of benzene, toluene, and chlorobenzene with cinchomeronic acid anhydride in the presence of AlCl3, has given in each case both possible isomers of the corresponding aroylpyridine carboxylic acid.It was found that the yields of reaction products and their isomeric compositions depend on the conditions of performing the reaction.The intramolecular cyclization on the isomeric keto acids in the presence of 2percent oleum has given 2-azaanthraquinone and chlorine derivatives of it.