74975-25-0

Upstream product

• 24015-80-3 3-methyl-4-benzylpyridine 
• 4664-08-8 cinchomeronic anhydride 
• 71-43-2 benzene 
• 100-44-7 benzyl chloride 
• 16214-99-6 N-benzyl-3-methyl-pyridinium chloride 
• 20260-53-1 pyridine-3-carbonyl chloride hydrochloride 
• 611-74-5 N,N-dimethylbenzamide 
• 849322-39-0 1-phenyl-1,3-dihydrofuro[3,4-c]pyridin-3-one 
• 88329-46-8 N,N-Diisopropyl-4-benzoyl-3-pyridinecarboxamide 
• 77924-01-7 N,N-diisopropylnicotinamide 
• 104084-46-0 4-[hydroxy(phenyl)methyl]-N,N-diisopropylnicotinamide 

Downstream Products

• 14548-46-0 4-Benzoylpyridine 
• 46492-08-4 benz[g]isoquinoline-5,10-dione 
• 104867-63-2 3-chloro-3-phenyl-6-azaphthalide hydrochloride 
• 175857-58-6 N-diphenylphosphinoylmethyl-N-methyl-3-benzoyl-2-pyridinecarboxamide 
• 104867-64-3 1-Chloro-1-phenyl-1H-furo[3,4-c]pyridin-3-one 
• 849322-40-3 1-hydroxy-1-phenyl-1,2-dihydro-3H-pyrrolo[3,4-c]pyridin-3-one 
• 104867-69-8 N-tert-butyl-4-benzoylnicotinamide 
• 104867-65-4 2-benzyl-3-hydroxy-3-phenyl-6-azaindolinone 

Relevant academic research and scientific papers

Studies on the 4-benzoylpyridine-3-carboxamide entity as a fragment model of the Isoniazid-NAD adduct

An ortho-metallatkm-electrophilic substitution sequence was employed as a key step to build the 4-benzoylpyridine framework. It was found that 4-benzoylpyridine-3-carboxamide and an N-pyridyl alkylated derivative both exist in a unique cyclized hemiamidal

Tricyclic thiazole and oxazole derivatives and pharmaceutical agents containing them

The present invention concerns thiazolo- 2,3-a!pyrrole and oxazolo- 1,2-a!pyrrole derivatives of formula I STR1 in which HET represents a heterocyclic ring with 3-7 ring atoms which can be substituted by one, two or three residues R1 which can be the same or different, Y represents an oxygen or sulphur atom, or a SO or SO2 group, X can be an oxygen or sulphur atom, R denotes an aliphatic residue with 1-9 C-atoms which can be substituted by phenyl or denotes a phenyl ring or a carbocyclic ring with 7-15 C atoms or a heterocyclic ring system each having 5 or 6 ring atoms, in which the aforementioned phenyl rings, carbocyclic rings or heterocyclic ring system can be substituted once or several times, if desired, and R1-R5 denote hydrogen or an aliphatic residue, as well as their tautomers, enantiomers, diastereomers and physiologically tolerated salts.

Heterocyclic compounds, their production and use as tachykinin reactor antagonists

A novel compound represented by the formula: STR1 wherein Ring A and Ring B respectively stands for an optionally substituted homo- or hetero-cyclic ring, and at least one of them stands for an optionally substituted heterocyclic ring stand; Ring C stands for an optionally substituted benzene ring; R stands for a hydrogen atom or an optionally substituted hydrocarbon residue; one of X and Y stands for --NR1 -- (R1 stands for a hydrogen atom or an optionally substituted hydrocarbon residue) or --O--, and the other stands for--CO-- or --CS--, or one of them stands for --N= and the other stands for =CR2 -- (R2 stands for a hydrogen atom, a halogen atom, an optionally substituted hydrocarbon residue, an optionally substituted amino group or an optionally substituted hydroxyl group); n denotes 1 or 2 or salts thereof which have an excellent tachykinin receptor antagonistic action and inhibitory action on plasma extravasation.

APPLICATIONS of ORGANOLITHIUM and RELATED REAGENTS in SYNTHESIS. Part IV. A General Study of the Reaction of N,N-Dialkylpyridinecarboxamides with Lithium Diisopropylamide

The reactions of the N,N-dialkylpyridinecarboxamides (1), (2) and (3) derived from picolinic, nicotinic and isonicotinic acids with lithium diisopropylamides have been examied.It is shown that in contrast with N,N-diethylpyridinecarboxamides (1a), (2a) an

SYNTHESIS OF 2-AZAANTRAQUINONE AND ITS DERIVATIVES

The acylation of benzene, toluene, and chlorobenzene with cinchomeronic acid anhydride in the presence of AlCl3, has given in each case both possible isomers of the corresponding aroylpyridine carboxylic acid.It was found that the yields of reaction products and their isomeric compositions depend on the conditions of performing the reaction.The intramolecular cyclization on the isomeric keto acids in the presence of 2percent oleum has given 2-azaanthraquinone and chlorine derivatives of it.