74994-62-0

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 60032-63-5 4-hydroxy-3-iodo-benzaldehyde 
• 100-39-0 benzyl bromide 
• 2314-37-6 3-iodo-4-methoxybenzaldehyde 
• 100-44-7 benzyl chloride 

Downstream Products

• 436-05-5 (±)-curine 
• 1209470-10-9 C₁₅H₁₁IO₃ 
• 1209470-11-0 C₁₅H₁₁IO₃ 
• 1209470-09-6 4'-benzyloxy-3'-iodoflavanone 
• 1209470-13-2 C₂₂H₁₇IO₄ 
• 1209470-12-1 C₂₉H₂₃IO₄ 
• 4397-53-9 p-benzyloxybenzaldehyde 
• 74994-63-1 6,6'-bis(benzyloxy)biphenyl-3,3'-dicarbaldehyde 

Relevant academic research and scientific papers

A Modular Access to (±)-Tubocurine and (±)-Curine - Formal Total Synthesis of Tubocurarine

Two consecutive Cu-catalyzed Ullmann-type C-O couplings permitted the first successful entry toward the curare alkaloids (±)-tubocurine and (±)-curine. Starting from vanillin, the synthetic sequence comprises 15 linear steps and includes a total of 24 transformations. In addition, the total synthesis of tubocurine represents a formal total synthesis of the famous arrow poison alkaloid tubocurarine.

Total synthesis of 3′,3?-binaringenin and related biflavonoids

The synthesis of natural 3++,3?-binaringenin and four related biflavonoids was performed in good overall yield (15-35%) starting from readily available phloroglucinol and 4-hydroxy- or 4-methoxybenzaldehyde. Preliminary results indicate that some of these compounds have an interesting activity against S. aureus. Georg Thieme Verlag Stuttgart.