75008-95-6Relevant academic research and scientific papers
Synthesis and biological evaluation of novel pyrazole derivatives as antibacterial agents
Daemi, Fariba,Allameh, Sadegh,Pordel, Mehdi
, p. 579 - 580,2 (2020/09/16)
The synthesis of a novel series of 5-[(X-benzoylamino)]-1-(2,4- dinitrophenyl)-1H-4-pyrazolecarboxamide derivatives is described. Their antibacterial activity (MIC) against methicillin-susceptible and methicillin-resistant Staphylococcus aureus (MRSA) wer
Design, synthesis, and structure-activity relationship study of 5-amido-1-(2,4-dinitrophenyl)-1H-4-pyrazolecarbonitrils as DD-carboxypeptidase/ penicillin-binding protein inhibitors with Gram-positive antibacterial activity
Sadeghian, Hamid,Sadeghian, Ali,Pordel, Mehdi,Rahimizadeh, Mohammad,Jahandari, Pooneh,Orafaie, Ala,Bakavoli, Mehdi
experimental part, p. 103 - 119 (2010/12/25)
In this study, we report the design, synthesis, and structure-activity relationships of a series of 5-amido-1-(2,4-dinitrophenyl)-1H-4- pyrazolecarbonitriles as DD-carboxypeptidase/penicillin-binding protein (PBP) inhibitors with Gram-positive antibacteri
Reactivity of 1-(2-nitrophenyl)-5-aminopyrazoles under basic conditions and synthesis of new 3-, 7-, and 8-substituted pyrazolo [5,1-c][1,2,4]benzotriazine 5-oxides, as benzodiazepine receptor ligands
Costanzo,Guerrini,Bruni,Selleri
, p. 1369 - 1376 (2007/10/02)
The reaction of 1-(2-nitrophenyl)-5-aminopyrazoles under basic conditions has been reinvestigated and the structures of the obtained pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides confirmed by spectroscopic means. In particular the different aromatic nucleophilic attack on 8-chloro derivatives 4a and 6a and 7-nitro derivatives 11a and 12a was determined. From these latter compounds unexpected (phenyl-ONN-azoxy)pyrazoles were isolated.
