75041-39-3

Upstream product

• 186581-53-3 diazomethane 
• 77-78-1 dimethyl sulfate 
• 2569-86-0 5,8-dihydroxy-7-methoxyflavanone 
• 67-64-1 acetone 
• 100-52-7 benzaldehyde 
• 91856-16-5 2'-hydroxy-3',4',6'-trimethoxychalcone 
• 5333-45-9 1,2,3,5-tetramethoxybenzene 
• 642-71-7 3,4,5-trimethoxyphenol 
• 91856-16-5 2E-1-(2'-hydroxy-3',4',6'-trimethoxyphenyl)-3-(phenyl)-prop-2-en-1-one 
• 7507-98-4 1-(2-hydroxy-3,4,6-trimethoxyphenyl)ethanone 

Downstream Products

• 2569-86-0 5,8-dihydroxy-7-methoxyflavanone 
• 54377-25-2 5?hydroxy?7,8?dimethoxyflavanone 
• 152172-45-7 5,7,8-trimethoxyflav-3-ene 

Relevant academic research and scientific papers

Efficient Access to Chromeno[4,3- b ]quinolines Related to Dependensin

We report a robust synthesis of novel chromeno[4,3- b ]quinoline derivatives structurally similar to the natural product dependensin. The target compounds are accessed through the acid-catalysed condensation of 2-aminoacetophenones or 2-aminochalcones with substituted flavanones, which are in turn obtained from 2-hydroxyacetophenones and benzaldehydes.

Acid catalyzed stereoselective rearrangement and dimerization of flavenes: synthesis of dependensin

Appropriately substituted flavenes undergo stereoselective rearrangement and dimerization when treated with methanolic hydrochloric acid to give benzopyranobenzopyrans. A rationale for the rearrangement is proposed. This synthetic methodology has been used for a high yield synthesis of the natural product dependensin.