75059-00-6

Basic information

• Product Name: 2-Propen-1-amine, 3-(2-nitrophenyl)-
• CAS NO: 75059-00-6
• Molecular Formula: C9H10N2O2
• Molecular Weight: 178.191
• Mol File: 75059-00-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-amine, 3-(2-nitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-amine, 3-(2-nitrophenyl)-(75059-00-6)
• EPA Substance Registry System: 2-Propen-1-amine, 3-(2-nitrophenyl)-(75059-00-6)

Safety Data

• Hazardous Substances Data: 75059-00-6(Hazardous Substances Data)

Upstream product

• 577-19-5 2-nitrophenyl bromide 
• 1466-88-2 2-nitrocinnamaldehyde 
• 1504-65-0 3-(2-nitrophenyl)prop-2-en-1-ol 
• 75059-03-9 N-(2-Nitrocinnamyl)phthalimide 
• 1466-88-2 2-nitrocinnamic aldehyde 
• 1504-65-0 2-nitrocinnamyl alcohol 

Downstream Products

• 132148-39-1 {3-[(E)-3-(2-Nitro-phenyl)-allylaminooxalyl]-1H-indol-2-yl}-acetic acid ethyl ester 
• 138956-09-9 Ethyl 3-<glyoxylyl>indole-2-acetate 
• 85753-43-1 staurosporine aglycone 
• 132148-42-6 4-(2'-Nitrophenyl)-2,3-dihydro-2H,6H-pyrrolo<3,4-c>carbazol-1-one 
• 138956-12-4 2,3,4,5-Tetrahydro-4-(2'-nitrophenyl)pyrrolo<3,4-c>carbazol-1-one 
• 128287-91-2 4-(2'-Nitrophenyl)-2,3-dihydro-2H,6H-pyrrolo<3,4-c>carbazol-1,3-dione 
• 138956-10-2 3-<glyoxylyl>indole-2-acetic Acid 
• 138956-11-3 3-N-(2'-Nitrocinnamyl)-3-oxopyrano<4,3-b>indole-1-carboxamide 
• 132148-40-4 {3-[(E)-3-(2-Nitro-phenyl)-allylaminooxalyl]-1H-indol-2-yl}-acetic acid 
• 132148-41-5 3-Oxo-3,5-dihydro-pyrano[4,3-b]indole-1-carboxylic acid [(E)-3-(2-nitro-phenyl)-allyl]-amide 
• 1380310-77-9 (E)-1-nitro-2-(3-phenylprop-1-enyl)benzene 
• 1397699-30-7 C₁₅H₁₃NO₄S 

Relevant articles and documents

Aminosilanes in organic synthesis. Hydrostannation of N,N-bis(trimethylsilyl)propargylamine. Facile and selective routes to (E)-allylic amines

The addition of tributyl tin hydride to N,N-bis(trimethylsilyl)propargylamine yielded E-1-tributylstannyl-3-prop-1-ene 2 in 90percent yield and 96percent stereochemical purity.The functional vinyl tin reagent 2 was shown to give short and selective access to primary allylic amines.The reactions of 2 with aryl and vinyl bromides in the presence of a palladium catalyst gave substituted E-allylic amines in high yields.The reaction of 2 with butyl lithium yielded E-γ-vinyl lithium from which selective access to E-allylic amines was obtained.Key words: silylamines / propargylamines / hydrostannation / vinyl tin / vinyl lithium / (E)-allylamines

A simple synthesis of primary E-allylic amines from 1-tributylstannyl-3-bis(trimethylsilyl)amino prop-1-ene

A facile and selective preparation of primary E-allylic amines is described from the readily available γ-amino vinylic tin reagent 2, either by using the direct palladium catalysed coupling of the vinyl tin moitie or via conversion to a γ-amino vinyl lithium reagent.