75113-60-9 Usage
Uses
Used in Pharmaceutical Synthesis:
5-(beta-hydroxyethyl)-4-methylthiazole-2-carboxylic acid is used as a precursor in the pharmaceutical industry for the synthesis of various pharmaceutical compounds. Its unique chemical structure allows for the creation of diverse therapeutic agents, contributing to the development of new medications.
Used in Industrial Processes as a Chelating Agent:
In the chemical industry, 5-(beta-hydroxyethyl)-4-methylthiazole-2-carboxylic acid is utilized as a chelating agent. Its ability to form stable complexes with metal ions makes it suitable for applications such as water treatment, detergents, and other processes where metal ion sequestration is required.
Used in Coordination Chemistry as a Ligand:
5-(beta-hydroxyethyl)-4-methylthiazole-2-carboxylic acid is employed as a ligand in coordination chemistry. Its coordination properties enable the formation of complexes with various metal ions, which can be used in catalysis, materials science, and other areas of research and development.
Used in Chemical Research and Development:
As a key building block, 5-(beta-hydroxyethyl)-4-methylthiazole-2-carboxylic acid is used in the research and development of new chemical compounds. Its reactivity and functional groups make it a valuable component in the synthesis of novel molecules with potential applications in various fields.
Used in the Creation of Diverse Chemicals and Pharmaceuticals:
5-(beta-hydroxyethyl)-4-methylthiazole-2-carboxylic acid is a vital component in the synthesis of a wide range of chemicals and pharmaceuticals. Its versatility and compatibility with various chemical reactions make it an essential ingredient in the development of innovative products across different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 75113-60-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,1,1 and 3 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 75113-60:
(7*7)+(6*5)+(5*1)+(4*1)+(3*3)+(2*6)+(1*0)=109
109 % 10 = 9
So 75113-60-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H9NO3S/c1-4-5(2-3-9)12-6(8-4)7(10)11/h9H,2-3H2,1H3,(H,10,11)
75113-60-9Relevant academic research and scientific papers
Biosynthesis of the thiamin thiazole in Bacillus subtilis: Identification of the product of the thiazole synthase-catalyzed reaction
Hazra, Amrita,Chatterjee, Abhishek,Begley, Tadhg P.
supporting information; experimental part, p. 3225 - 3229 (2009/07/30)
In this paper, we describe an optimized reconstitution of the thiamin thiazole synthase (ThiG) catalyzed reaction and demonstrate that the enzymatic product is an unanticipated dearomatized thiazole tautomer.
The Biosynthesis of Thiamine. Syntheses of -1-Deoxy-D-threo-2-pentulose and Incorporation of this Sugar in Biosynthesis of Thiazole by Escherichia coli Cells
David, Serge,Estramareix, Bernard,Fischer, Jean-Claude,Therisod, Michel
, p. 2131 - 2138 (2007/10/02)
Non-growing, washed cells of Escherichia coli, depressed for the synthesis of thiamine, were incubated in the presence of -1-deoxy-D-threo-2-pentulose (9) in a medium containing the pyrimidine moiety of thiamine, L-tyrosine, and glucose.The thiamine thus biosynthesized was extracted and cleaved to give 5-(2-hydroxyethyl)-4-methylthiazole (HET) which was examined as the trifluoroacetate derived by electron-impact mass spectrometry.The distribution of the label in the fragments indicated that the pentulose (9) was a precursor of the C5-chain of HET without C-C bond cleavage.Several routes to 1-deoxypentuloses are described.Condensation of 2,4-O-benzylidene-D-threose (23) with trideuteriomethylmagnesium iodide gave the protected 1-deoxypentitols (24) and (25).Brominolysis of the mixed dibutylstannylidenes then afforded -3,4-O-benzylidene-1-deoxy-D-threo-2-pentulose (26), which was converted into the free sugar (9) by acidic hydrolysis. 1-Deoxy-D-erythro-2-pentulose was prepared in similar manner.Condensation of 2-(-methyl)-1,3-dithian with 2,3-O-isopropylidene-D-glyceraldehyde, followed by a C-3 epimerization step also led, after deprotection, to a mixture of -1-deoxy-D-erythro- and -1-deoxy-D-threo-2-pentulose, (5) and (6).
