75120-08-0Relevant articles and documents
MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS
-
Paragraph 00554; 00784; 00785, (2018/09/12)
Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidase (SpsB), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.