75129-79-2Relevant academic research and scientific papers
Synthesis and evaluation of substituted quinazolone derivatives for antibacterial, antifungal, and antiacetylcholinesterase activities
Gupta,Misra
, p. 1313 - 1317 (1980)
The synthesis of new 6-bromo- and 6,8dibromo-2-[N-(2'-alkyl -1',3',4' -thiadiazol -5' -yl)carbamoylmethylthiol] -3- aryl/cyclohexyl-4-(3H)-quinazolones is described. The synthesized derivatives were screened for antibacterial, antifungal, and antiacetylcholinesterase activities in vitro. Most of the compounds exhibited significant biological activity. The relation between their biological activity and chemical structure was studied.
