75136-50-4Relevant academic research and scientific papers
One-pot synthesis of trisubstituted 1,2-amino alcohols from deprotonated α-amino nitriles
Kison, Coralie,Opatz, Till
, p. 2740 - 2745 (2008)
A short synthesis of N,1,2-trisubstituted vicinal amino alcohols by 1,2-addition of deprotonated N-monosubstituted α-amino nitriles to aldehydes and subsequent one-pot reduction of the intermediates with borane-THF is described. This procedure leads to the predominant formation of the anti-configured products. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.
