75220-77-8

Upstream product

• 95-54-5 1,2-diamino-benzene 
• 959-33-1 3-(4-methoxyphenyl)-1-phenylprop-2-en-1-one 
• 88-74-4 2-nitro-aniline 
• 22252-15-9 trans-4-methoxychalcone 
• 22966-22-9 (E)-1-(4-chlorophenyl)-3-phenyl-2-propen-1-one 
• 116460-49-2 1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-ol 
• 98-86-2 acetophenone 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 716-79-0 2-phenyl-1H-benzoimidazole 
• 2620-81-7 2-(4-methoxyphenyl)-1H-benzimidazole 

Relevant academic research and scientific papers

Graphite oxide: A metal free highly efficient carbocatalyst for the synthesis of 1,5-benzodiazepines under room temperature and solvent free heating conditions

Graphite Oxide (GO), an attractive metal free carbocatalyst, was employed as a green and highly efficient catalytic system for the synthesis of 1,5-benzodiazepines. The reaction was studied at room temperature as well as at 80°C under solvent free heating

Construction of the 1,5-Benzodiazepine Skeleton from o-Phenylendiamine and Propargylic Alcohols via a Domino Gold-Catalyzed Hydroamination/Cyclization Process

The gold-catalyzed reaction of o-phenylendiamine with propargylic alcohols affords 1,5-benzodiazepines bearing different substituents on the 2 and 4 positions. The method allows even for the selective preparation of 4-substituted 1,5-benzodiazepine derivatives.

A new and efficient one-pot solid-supported synthesis of 1,2,4,6-tetraaryl-1,4-dihydropyridines

1,2,4,6-Tetraaryl-1,4-dihydropyridines were obtained by the one-pot reaction of chalcones and substituted anilines on the surface of Bi(III)nitrate-Al2O3. The reaction seems to proceed via β-oxygenation of Bi(III) enolised chalcones followed by Michael addition and heteroannulation with simultaneous retro aldol disproportionation. The presence of the ring-activating groups at ortho and para positions in the aniline seems to be essential for the reaction.

Protic acidic ionic liquids promoted formation of 1,5-benzodiazepines: Remarkable effects of cations and anions on their performances

A series of protic acidic ionic liquids have been used as solvents and catalysts for the synthesis of 1,5-benzodiazepines. Success of the condensation appears to lie in the choice of cation-anion combinations and the ionic liquid [HBIm]CF3SOsu

SbCl3-Al2O3-catalyzed, solvent-free, one-pot synthesis of benzo[b]1,4-diazepines

This article explores the use of antimony(III) chloride adsorbed on neutral alumina as an efficient catalyst for the one-pot synthesis of benzo[b]1,4-diazepines (83-94%) under solvent-free conditions. The process is easy, efficient, ecofriendly, and econo

[BPy]HSO4 acidic ionic liquid as a novel, efficient, and environmentally benign catalyst for synthesis of 1,5-benzodiazepines under mild conditions

A novel and simple ionic liquid methodology for the synthesis of 1,5-benzodiazepines is described. 1-Butylpyridinium hydrogen sulphate ([BPy]HSO4), an acidic room-temperature ionic liquid, as a novel and efficient catalyst, was synthesized and

Solvent-free synthesis of 1,5-benzothiazepines and benzodiazepines on inorganic supports

1,5-Benzothiazepines and 1,5-benzodiazepines have been synthesized in solvent-free conditions from chalcones and o-aminothiophenol or o-phenylenediamine in the presence of inorganic support. Silica gel was found to be an effective support for the synthesi

Derivatives of 2,3-dihydro-1H-1,5-benzodiazepine from o-nitroanilines and chalcones induced by low-valent titanium

2,3-Dihydro-1H-1,5-benzodiazepines have been prepared in good yield by reaction of o-nitroanilines with chalcones induced by the TiCl4-Sm-THF system under mild reaction conditions.

NEW ASPECTS OF THE CHEMISTRY OF 2,3-DIHYDRO-1H-1,5-BENZODIAZEPINE

Under basic catalysis conditions the reaction of 4- and 4'-substituted chalcones with o-phenylenediamine leads to 2,3-dihydro-2,4-diaryl-1H-1,5-benzodiazepines; β-amino adducts, the ability of which to undergo intramolecular condensation increases as the