752243-45-1Relevant academic research and scientific papers
Potent and orally bioavailable non-peptide antagonists at the human bradykinin B1 receptor based on a 2-alkylamino-5-sulfamoylbenzamide core
Ritchie, Timothy J.,Dziadulewicz, Edward K.,Culshaw, Andrew J.,Müller, Werner,Burgess, Gillian M.,Bloomfield, Graham C.,Drake, Gillian S.,Dunstan, Andrew R.,Beattie, David,Hughes, Glyn A.,Ganju, Pam,McIntyre, Peter,Bevan, Stuart J.,Davis, Clare,Yaqoob, Mohammed
, p. 4642 - 4644 (2004)
The bradykinin B1 receptor is rapidly induced after inflammation or tissue trauma and appears to play an important role in the maintenance of hyperalgesia in inflammatory conditions. Here, we describe the optimization process to identify novel,
