75230-41-0Relevant academic research and scientific papers
Chemoselective and ligand-free aerobic oxidation of benzylic alcohols to carbonyl compounds using alumina-supported mesoporous nickel nanoparticle as an efficient recyclable heterogeneous catalyst
Das, Asit Kumar,Nandy, Sneha,Bhar, Sanjay
, (2021/05/10)
An economically efficient and operationally simple ligand-free protocol for the chemoselective oxidation of benzylic alcohols to carbonyl compounds has been developed using alumina-supported nickel nanoparticles as a stable recyclable heterogeneous catalyst along with potassium tert-butoxide in the presence of aerial oxygen as an eco-friendly oxidant. The aliphatic alcohols remained unaffected under the present condition. Excellent chemoselectivity has also been demonstrated through intermolecular and intramolecular competition experiments. This protocol accommodates a diverse range of substituents with the tolerance of various sensitive moieties during the reaction. The catalyst could be recovered by filtration and reused consecutively without any significant loss in the catalytic activity. Moreover, the heterogeneity of the catalyst has also been established by the “hot filtration method (Sheldon's test)”.
SYNTHESIS OF ACYL 1-ACETOXY-2-PHENOXYETHANES AND THE CORRESPONDING HYDROXY DERIVATIVES
Lukac, Ivan,Zvara, Ivan,Kulickova, Magdalena,Hrdlovic, Pavol
, p. 1826 - 1830 (2007/10/02)
Acyl 1-acetoxy-2-phenoxyethanes Ia-Id were prepared by aluminium chloride or polyphosphoric acid-catalyzed Friedel-Crafts acylation.Subsequent hydrolysis gave the corresponding alcohols IIa-IId.The formation of ortho-isomers during acylation was not observed.
