75243-71-9Relevant academic research and scientific papers
Dienyl homoallyl alcohols via palladium catalyzed ene-type reaction of aldehydes with 1,3-dienes
Fukushima, Masahiro,Takushima, Daiki,Kimura, Masanari
supporting information; experimental part, p. 16346 - 16348 (2011/02/22)
The combination of Pd catalyst and Xantphos ligand in the presence of Et3B nicely promotes the allylation of aldehydes with conjugated dienes to provide dienyl homoallyl alcohols in excellent yields. The reaction occurs selectively at the C-C double bond bearing higher electron density.
In Turn or in Reverse Palladium-Catalyzed Carbonyl Allylation and Diels-Alder Reaction by 2-Methylene-3-buten-1-ol
Masuyama, Yoshiro,Fuse, Manabu,Kurusu, Yasuhiko
, p. 1199 - 1202 (2007/10/02)
Using PdCl2(PhCN)2-SnCl2, 2-methylene-3-buten-1-ol causes carbonyl allylation of various aldehydes to afford 1-substituted-3-methylene-4-penten-1-ols, the Diels-Alder reaction of those with dienophiles produces 1-(2-hydroxyethyl)cyclohexenes.Diels-Alder reaction of 2-methylene-3-buten-1-ol with dienophiles followed by carbonyl allylation produces isomeric 1-methylene-2-(hydroxymethyl)cyclohexanes.
REGIOSPECIFIC CYCLOADDITION REACTIONS USING FUNCTIONALIZED ISOPRENYLSILANE AND RELATED COMPOUNDS
Hosomi, Akira,Sakata, Yasuyuki,Sakurai, Hideki
, p. 5175 - 5178 (2007/10/02)
1-Alkoxy-3-trimethylsilylmethyl- and 1-alkoxy-3-trimethylsilyl-l,3-butadienes (1) were newly prepared.The cycloaddition reactions of 1 with various dienophiles including heterodienophiles were found to proceed very smoothly in a perfectly regiospecific mo
CHEMISTRY OF THE ORGANOSILICON COMPOUNDS-165 2-TRIMETHYLSILYL-METHYL-1, 3-BUTADIENE-A VERSATILE BUILDING BLOCK FOR TERPENE SYNTHESIS
Sakurai, Hideki,Hosomi, Akira,Saito, Masaki,Sasaki, Koshi,Iguchi, Hirokazu,et al.
, p. 883 - 894 (2007/10/02)
Two types of synthetically useful reactions of 2-trimethylsilylmethyl-1,3-butadiene (7) are discussed.Reactions of 7 with acid chlorides, aldehydes, ketones and acetals activated by a Lewis acid give isoprenylated compounds, while 7 undergoes the Diels-Alder reaction whit dienophiles.High regiospecificity of the reaction qualifies 7 for a versatile building block of terpene synthesis.
