75270-15-4Relevant academic research and scientific papers
Compounds and compositions as lxr modulators
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Page/Page column 10, (2010/01/31)
The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of liver X receptors (LXRs).
Selective recognition of sodium cyanide and potassium cyanide by diaza-crown ether-capped Zn-porphyrin receptors in polar solvents
Liu, Hui,Shao, Xue-Bin,Jia, Mu-Xin,Jiang, Xi-Kui,Li, Zhan-Ting,Chen, Guang-Ju
, p. 8095 - 8100 (2007/10/03)
Two new ditopic porphyrin receptors Zn1, incorporating a diaza-15-crown-5 unit, and Zn2, incorporating a diaza-18-crown-6 unit, have been prepared and characterized. UV-vis study in polar methanol has revealed that Zn1 is able to selectively recognize sodium cyanide over potassium cyanide (the ratio of their binding constant is ca. 56), whereas Zn2 exhibits a higher binding affinity for potassium cyanide over sodium cyanide (the ratio of their binding constant is ca. 12). In contrast, both receptors display substantially weaker binding affinity for sodium thiocyanate and potassium thiocyanate presumably due to a monotopic binding fashion.
