216082-34-7Relevant academic research and scientific papers
Compounds and compositions as lxr modulators
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Page/Page column 10, (2010/01/31)
The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of liver X receptors (LXRs).
Synthesis and properties of new 2-alkyl-1,4-benzoxazepine derivatives. Part III. Synthesis and cyclization of 2-(2-carboxyphenoxy)alkanamides
Kwiecien
, p. 2254 - 2260 (2007/10/03)
A series of novel 2-(2-carboxyphenoxy)aIkanamides 4a-f have been obtained as result of condensation of salicylaldehydes with 2-halo esters, amination of prepared esters 1a-f with methylamine followed by oxidation of amides 3a-f with sodium chlorite. The intramolecular cyclization of amides 4a-f to 1,4-benzoxazepin-3,5-dione system has been investigated.
