853759-49-6

Usage

Chemical Properties

White Solid

Upstream product

• 128217-62-9 (S)-ethyl 2-(N-(tert-butoxycarbonyl)amino)-3-(3,4-dimethoxyphenyl)propanoate 
• 1421282-26-9 N-(tert-butoxycarbonyl)-3,4-(dimethoxy)-6-(iodo)-L-phenylalanine 
• 1421282-27-0 N-(tert-butoxycarbonyl)-3,4-(dimethoxy)-6-(iodo)-L-phenylalanine methyl ester 
• 1421282-25-8 ethyl (S)-2-((tert-butoxycarbonyl)amino)-3-(2-iodo-4,5-dimethoxyphenyl)propanoate 
• 1421282-31-6 N-(tert-butoxycarbonyl)-3,4-dimethoxy-6-(1,3,2-dioxaborinane-5,5-dimethyl)-L-phenylalanine methyl ester 
• 1421282-68-9 C₁₇H₂₄AgNO₆ 
• 853759-47-4 methyl-2-[(tert-butoxycarbonyl)amino]-3-(2-fluoro-4,5-dimethoxyphenyl)prop-2-enoate 

Downstream Products

• 75290-51-6 3,4-dihydroxy-6-fluoro-L-phenylalanine 

Relevant academic research and scientific papers

Fluorination of an arylboronic ester using [18F]selectfluor bis(triflate): Application to 6-[18F]fluoro-l-DOPA

The Ag-mediated electrophilic [18F]fluorination of an arylboronic ester is reported. This new radiochemical transformation uses [ 18F]selectfluor bis(triflate) in acetone. The process gave 6-[ 18F]fluoro-l-DOPA with a RCY of 19 ± 12% and a specific activity of 2.6 ± 0.3 GBq μmol-1.

Method for making fluorine labled L-Dopa

The invention relates to a method for preparing F-Dopa and 18F-Dopa and intermediates that are useful in the method. The invention is a method that synthesizes F-Dopa and 18F-Dopa in good yield with high enantiopurity without the nee