752969-45-2Relevant academic research and scientific papers
HETEROCYCLIC COMPOUND
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Paragraph 0564; 0780; 0781, (2017/04/11)
The present invention provides a heterocyclic compound having a CDK8 and/or CDK19 inhibitory effect. The present invention provides a compound represented by formula (I) (in the formula, the symbols are as defined in the description) or a salt thereof.
Heterocyclic compound
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Paragraph 0238; 0239, (2017/09/28)
本發明提供一種具有CDK8/19抑制活性之雜環化合物。本發明提供一種如下式代表之化合物(其中各代號均如本文之定義)或其鹽。 The present invention provides a heterocyclic compound possessing CDK8/19 inhibitory activity. The present invention provides a compound represented by the formula wherein each symbol is as defined herein, or a salt thereof.
Two-step one-pot synthesis of benzoannulated spiroacetals by Suzuki-Miyaura coupling/acid-catalyzed spiroacetalization
Butkevich, Alexey N.,Corbu, Andrei,Cossy, Janine,Meerpoel, Lieven,Bonnet, Pascal,Stansfield, Ian,Angibaud, Patrick
supporting information, p. 4998 - 5001,4 (2012/12/12)
Substituted benzoannulated spiroacetals were prepared from (2-haloaryl)alkyl alcohols and dihydropyranyl or dihydrofuranyl pinacol boronates using a Suzuki-Miyaura coupling followed by an acid-catalyzed spirocyclization. Application of the reaction to a glycal boronate provides an approach to annulated spiroacetals in enantiopure form.
A new family of halogen-chelated hoveyda-grubbs-type metathesis catalysts
Barbasiewicz, Michal,Michalak, Michal,Grela, Karol
supporting information, p. 14237 - 14241,5 (2020/09/16)
Coordination, not insertion: New ruthenium benzylidenes with a chelating halogen atom were easily prepared and showed excellent stability and activity as metathesis catalysts (see figure). Structure-activity studies reveal that strength of the ruthenium-halogen interaction can be tuned across a wide range to set up a family of latent to active catalysts. Copyright
