75308-65-5

Basic information

• Product Name: N-(2-diisopropylaminoethyl)-N-(4,6-dimethyl-2-pyridyl)-N',N'-dimethylurea
• Synonyms: N-(2-diisopropylaminoethyl)-N-(4,6-dimethyl-2-pyridyl)-N',N'-dimethylurea;L-634366;N,N-Dimethyl-N'-[2-(diisopropylamino)ethyl]-N'-(2,4-dimethyl-6-pyridinyl)urea
• CAS NO: 75308-65-5
• Molecular Formula: C18H32 N4 O
• Molecular Weight: 0
• Mol File: 75308-65-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 433.9°C at 760 mmHg
• Flash Point: 216.2°C
• Appearance: /
• Density: 1.02g/cm³
• Vapor Pressure: 9.9E-08mmHg at 25°C
• Refractive Index: 1.532
• CAS DataBase Reference: N-(2-diisopropylaminoethyl)-N-(4,6-dimethyl-2-pyridyl)-N',N'-dimethylurea(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-diisopropylaminoethyl)-N-(4,6-dimethyl-2-pyridyl)-N',N'-dimethylurea(75308-65-5)
• EPA Substance Registry System: N-(2-diisopropylaminoethyl)-N-(4,6-dimethyl-2-pyridyl)-N',N'-dimethylurea(75308-65-5)

Safety Data

• Hazardous Substances Data: 75308-65-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C18H32N4O/c1-13(2)21(14(3)4)9-10-22(18(23)20(7)8)17-12-15(5)11-16(6)19-17/h11-14H,9-10H2,1-8H3

Upstream product

• 84369-57-3 N-<2-(diisopropylamino)ethyl>-N-(4,6-dimethyl-2-pyridyl)acetamide 
• 4261-68-1 1-chloro-2-diisopropylaminoethane hydrochloride 
• 5407-88-5 N-(4,6-dimethyl-2-pyridinyl)acetamide 
• 63763-73-5 2-<<2-(diisopropylamino)ethyl>amino>-4,6-dimethylpyridine 
• 79-44-7 N,N-Dimethylcarbamoyl chloride 

Relevant articles and documents

Inhibitors of gastric acid secretion: Antisecretory 2-pyridylurea derivatives

A series of aminoalkyl-substituted pyridylureas has been prepared and evaluated as inhibitors of gastric acid secretion. N,N-Dimethyl-N'-[2-(diisopropylamino)ethyl-N'-(4,6-dimethyl-2-pyridyl)urea (8g) was the most potent example of the class. Comparison of this compound with cimetidine showed it to be equipotent in dogs stimulated with gastrin tetrapeptide but approximately half as potent in dogs stimulated with histamine. Inhibition of secretion does not appear to result from antagonism of the histamine H2 receptor, since the compounds show only weak inhibition of the H2 receptor in vitro.