5407-88-5 Usage
Uses
Used in Pharmaceutical Synthesis:
N-(4,6-dimethylpyridin-2-yl)acetamide is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic effects.
Used in Organic Compounds Synthesis:
N-(4,6-dimethylpyridin-2-yl)acetamide serves as a building block in the creation of other organic compounds, facilitating the advancement of organic chemistry and the discovery of novel chemical entities.
Used in Coordination Chemistry as a Ligand:
N-(4,6-dimethylpyridin-2-yl)acetamide is utilized as a ligand in coordination chemistry, playing a crucial role in the formation of coordination complexes that have applications in various fields, including catalysis and materials science.
Used in Research and Development Laboratories:
It is employed as a reagent in research and development settings to explore its properties and potential uses, contributing to the advancement of scientific knowledge and the creation of innovative applications.
Used in Medicinal Chemistry and Drug Discovery:
Due to its structural features, N-(4,6-dimethylpyridin-2-yl)acetamide may have applications in medicinal chemistry, where it could be instrumental in the design and discovery of new drugs with improved therapeutic profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 5407-88-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,0 and 7 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 5407-88:
(6*5)+(5*4)+(4*0)+(3*7)+(2*8)+(1*8)=95
95 % 10 = 5
So 5407-88-5 is a valid CAS Registry Number.
5407-88-5Relevant academic research and scientific papers
Non-acidic anti-inflammatory compounds: activity of N-(4,6-dimethyl-2-pyridinyl) benzamides and derivatives
Robert-Piessard, Sylvie,Le Baut, Guillaume,Courant, Jacqueline,Brion, Jean-Daniel,Sparfel, Louis,et al.
, p. 9 - 19 (2007/10/02)
The inhibition of the carragenin-induced rat-paw edema by previously synthesized N-(4,6-dimethyl)-2-pyridinyl) benzamides was evaluated.Amoung the 29 tested compounds, secondary benzamides 1, 12 and tertiary benzamide 60 exhibited a significant anti-inflammatory activity.It prompted us to envision a pharmacomodulation in this series by structural modifications on the homocycle, the amide function and the heterocycle.Although benzamide 38, acetamide 50 and benzylamine 56 elicited marked inhibitory activity, none was more active than N-(4,6-dimethyl-2-pyridinyl) benzamide 1. The mechanism of the anti-inflammatory action of 1 was investigated.The results showed that this molecule reduced eicosanoid biosynthesis but was unable to reduce cyclooxygenase or lipoxygenase activities.Although it did not directly block phospholipase activity, however, an inhibitory process at this level is likely.
Synthesis and Central Dopaminergic Effects of N-(4,6-Dimethyl-2-pyridinyl)benzamides
Bouhayat, Said,Piessard, Sylvie,Baut, Guillaume Le,Sparfel, Louis,Petit, Jean-Yves,et al.
, p. 555 - 559 (2007/10/02)
N-(4,6-Dimethyl-2-pyridinyl)benzamides 1-24 and the corresponding tertiary derivatives 29-33 were synthesized and studied for possible dopamine-inhibitory properties by testing their effect on motility of naive and reserpinized mice.Unlike the orthopramid
