5407-88-5

Basic information

• Product Name: N-(4,6-dimethylpyridin-2-yl)acetamide
• CAS NO: 5407-88-5
• Molecular Formula: C₉H₁₂N₂O
• Molecular Weight: 164.2044
• Mol File: 5407-88-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 326.1°C at 760 mmHg
• Flash Point: 151°C
• Density: 1.107g/cm³
• Vapor Pressure: 0.00022mmHg at 25°C
• Refractive Index: 1.564
• CAS DataBase Reference: N-(4,6-dimethylpyridin-2-yl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4,6-dimethylpyridin-2-yl)acetamide(5407-88-5)
• EPA Substance Registry System: N-(4,6-dimethylpyridin-2-yl)acetamide(5407-88-5)

Safety Data

• Hazardous Substances Data: 5407-88-5(Hazardous Substances Data)

Usage

General Description

N-(4,6-dimethylpyridin-2-yl)acetamide is a chemical compound with the molecular formula C10H13N2O. It is an organic compound that contains a pyridine ring with two methyl groups at the 4 and 6 positions, as well as an acetamide group. This chemical is commonly used in the synthesis of pharmaceuticals and other organic compounds. It can act as a ligand in coordination chemistry and is also used in research and development laboratories for various purposes. It may have potential applications in the field of medicinal chemistry and drug discovery due to its structure and properties. Overall, N-(4,6-dimethylpyridin-2-yl)acetamide is an important chemical reagent with a range of potential uses in the scientific and pharmaceutical industries.

Upstream product

• 5407-87-4 2-Amino-4,6-dimethylpyridine 
• 108-24-7 acetic anhydride 

Downstream Products

• 1266119-24-7 2-amino-4-methyl-picolinic acid methyl ester 
• 75308-37-1 2-{2-[N-(2-Benzyloxyethyl)-N-methylamino]ethylamino}-4,6-dimethylpyridine 
• 84369-44-8 N-Benzyl-N'-(4,6-dimethyl-pyridin-2-yl)-N-isopropyl-ethane-1,2-diamine 
• 84369-60-8 N-(5-chloro-4,6-dimethyl-2-pyridyl)acetamide 
• 75308-65-5 N,N-Dimethyl-N'-(2-diisopropylamino-ethyl)-N'-(4-ethyl-<2>pyridyl)-harnstoff 
• 84369-65-3 N,N-Dimethyl-N'-<(2-isopropylbenzylamino)-ethyl)-N'-(4,6-dimethyl-<2>pyridyl)-harnstoff 
• 100868-73-3 2-Amino-4,6-dimethylpyridin-1-oxid 
• 89856-44-0 2-amino-5-bromo-4,6-dimethylpyridine 
• 89694-55-3 5-bromo-4,6-dimethylpyridin-2-ol 
• 94843-75-1 N-ethyl-N-(4,6-dimethyl-2-pyridinyl)-4-fluorobenzamide 
• 94843-76-2 3-Chloro-N-(4,6-dimethyl-pyridin-2-yl)-N-ethyl-benzamide 
• 94843-73-9 N-ethyl N-(4,6-dimethyl 2-pyridinyl)benzamide 

Relevant articles and documents

Non-acidic anti-inflammatory compounds: activity of N-(4,6-dimethyl-2-pyridinyl) benzamides and derivatives

The inhibition of the carragenin-induced rat-paw edema by previously synthesized N-(4,6-dimethyl)-2-pyridinyl) benzamides was evaluated.Amoung the 29 tested compounds, secondary benzamides 1, 12 and tertiary benzamide 60 exhibited a significant anti-inflammatory activity.It prompted us to envision a pharmacomodulation in this series by structural modifications on the homocycle, the amide function and the heterocycle.Although benzamide 38, acetamide 50 and benzylamine 56 elicited marked inhibitory activity, none was more active than N-(4,6-dimethyl-2-pyridinyl) benzamide 1. The mechanism of the anti-inflammatory action of 1 was investigated.The results showed that this molecule reduced eicosanoid biosynthesis but was unable to reduce cyclooxygenase or lipoxygenase activities.Although it did not directly block phospholipase activity, however, an inhibitory process at this level is likely.