7531-76-2

Usage

Uses

Used in Food Industry:
2-Acetyl-4,5-dimethylthiazole is used as a flavoring agent for its unique aroma, adding a roasted, nutty, or popcorn-like scent to various food products such as baked goods, cereal, and dairy products.
Used in Fragrance Industry:
In the fragrance industry, 2-acetyl-4,5-dimethylthiazole is used as a scent component to impart a roasted, nutty aroma to perfumes and colognes, enhancing their olfactory profiles.
Used in Pharmaceutical Research:
2-Acetyl-4,5-dimethylthiazole is being studied for its potential therapeutic applications, particularly in cancer treatment. Its role in modulating oncological signaling pathways and its ability to inhibit tumor growth are under investigation.
Used in Antimicrobial Applications:
Additionally, 2-ACETYL-4,5-DIMETHYLTHIAZOLE is being explored for its antimicrobial properties, with research focusing on its capacity to inhibit the growth of harmful bacteria, which could have implications for various medical and hygiene applications.

InChI:InChI=1/C7H9NOS/c1-4-6(3)10-7(8-4)5(2)9/h1-3H3

Upstream product

• 3581-91-7 4,5-Dimethylthiazole 
• 925-90-6 ethylmagnesium bromide 
• 78191-00-1 N-Methoxy-N-methylacetamide 
• 141-78-6 ethyl acetate 
• 127-19-5 N,N-dimethyl acetamide 
• 75-07-0 acetaldehyde 
• 110-05-4 di-tert-butyl peroxide 
• 201230-82-2 carbon monoxide 

Relevant academic research and scientific papers

Carbonylative Acetylation of Heterocycles

Herein, a new procedure for the carbonylative acetylation of heterocycles has been developed. In this process, organic peroxide acts as the methyl source. Various heterocycles were transformed into the corresponding methyl heterocyclic ketones in moderate to good yields.

Direct C-2 acylation of thiazoles with aldehydes via metal- and solvent-free c-h activation in the presence of tert-butyl hydroperoxide

A novel and efficient methodology for the synthesis of heteroaryl ketones by C-H activation of aldehydes and thiazoles is developed. The reaction occurs smoothly, under metal-, acid- and solvent-free conditions using tert-butyl hydroperoxide as the oxidant under an air atmosphere, to afford a wide range of heteroaryl ketones in moderate to good yields. The sp2 C-H bonds in the aldehyde and thiazole undergo direct oxidative cross-coupling, resulting in C-2 acylation of the azole. Georg Thieme Verlag Stuttgart · New York.

New 1,2,4-triazine derivatives and biological applications thereof

The invention relates to new 1,2,4-triazine derivatives of formula (I): wherein A, B, R2 and Y are defined in the application, their preparation and intermediates, their use as drugs and pharmaceutical compositions and associations containing them. The compounds of formula (I) are capable of inhibiting bacterial heptose synthesis.

QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES INHIBITING AUTOPHOSPHORYLATION OF MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR

An objective of the present invention is to provide compounds which have inhibitory activity against autophosphorylation of macrophage colony-stimulating factor receptors. The compounds of the present invention are represented by formula (I) and salt and solvate thereof: wherein X represents CH or N; Z represents O or S; R1, R2, and R3 represent H, optionally substituted alkoxy or the like; R4 represents H; R5, R6, R7, and R8 represent H, halogen, alkyl, alkoxy, trifluoromethyl or the like; R9 and R10 represent H, alkyl or the like; and any one of R11 and R12 represents H with the other representing alkyl and R13 represents an optionally substituted carbocyclic or heterocyclic ring or the like, or R11 represents H and R12 and R13 combine together to form a bicyclic carbocyclic ring.

THIAZOLES USEFUL AS INHIBITORS OF PROTEIN KINASES

The present invention relates to compounds useful of inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.