75318-34-2

Basic information

• Product Name: 3-oxo-2-phenylmethylidene-2,3-dihydrobenzo[b]furan
• Synonyms: 3-oxo-2-phenylmethylidene-2,3-dihydrobenzo[b]furan
• CAS NO: 75318-34-2
• Molecular Weight: 222.243
• Mol File: 75318-34-2.mol
• Article Data: 31

Chemical Properties

• CAS DataBase Reference: 3-oxo-2-phenylmethylidene-2,3-dihydrobenzo[b]furan(CAS DataBase Reference)
• NIST Chemistry Reference: 3-oxo-2-phenylmethylidene-2,3-dihydrobenzo[b]furan(75318-34-2)
• EPA Substance Registry System: 3-oxo-2-phenylmethylidene-2,3-dihydrobenzo[b]furan(75318-34-2)

Safety Data

• Hazardous Substances Data: 75318-34-2(Hazardous Substances Data)

Upstream product

• 7169-34-8 3-oxo-2,3-dihydrobenzo[b]furan 
• 100-52-7 benzaldehyde 
• 39729-11-8 2'-hydroxychalcone dibromides 
• 93011-74-6 2-benzyl-2-methoxy-benzofuran-3-one 
• 223511-19-1 1-[2-(tert-butyldimethylsilyloxy)phenyl]-3-phenylprop-2-yn-1-one 
• 90-02-8 salicylaldehyde 
• 109365-86-8 1-(o-hydroxyphenyl)-3-phenylpropargylic alcohol 
• 533-58-4 2-Iodophenol 
• 201230-82-2 carbon monoxide 
• 536-74-3 phenylacetylene 
• 75630-75-0 (Z)-α-bromo-2'-hydroxychalcone 
• 16619-68-4 1-(2-hydroxyphenyl)-3-phenylprop-2-yn-1-one 
• 888-12-0 (E)-2'-hydroxy-chalcone 
• 95-56-7 2-hydroxybromobenzene 

Downstream Products

• 65-85-0 benzoic acid 
• 4265-14-9 2-benzylbenzofuran 
• 24114-57-6 3-(2-hydroxyphenyl)-1-phenyl-1-propene 
• 35405-25-5 trans-2-benzylidene-2H-benzofuran-3-one epoxide 
• 58202-26-9 2-benzyl-3-oxo-2,3-dihydrobenzo[b]furan 
• 440633-77-2 2-(2-benzylbenzo[b]furan-3-yl)acetonitrile 
• 75793-89-4 C₁₆H₁₄N₂OS 
• 1391069-08-1 3-(4-phenylbenzofuro[3,2-b]pyridin-2-yl)coumarin 
• 1391069-02-5 3-(4-phenylbenzofuro[3,2-b]pyridin-2-yl)coumarin 
• 1391069-14-9 3-(4-phenylbenzofuro[3,2-b]pyridin-2-yl)coumarin 
• 1510838-37-5 4-phenyl-2-(pyridin-2-yl)benzofuro[3,2-b]pyridine 
• 73552-34-8 2,4-diphenylbenzofuro[3,2-b]pyridine 
• 1510838-38-6 2-(furan-2-yl)-4-phenylbenzofuro[3,2-b]pyridine 
• 1510838-39-7 4-phenyl-2-(thiophen-2-yl)benzofuro[3,2-b]pyridine 

Relevant articles and documents

Assigning regioisomeric or diastereoisomeric relations of problematic trisubstituted double-bonds through heteronuclear 2D selective J-resolved NMR spectroscopy

Although one of the first 2D NMR methods, but so far neglected, selective J-resolved NMR spectroscopy offers a unique opportunity to help organic chemists in structure elucidation, avoiding natural and non-natural product misassignments. This NMR method i

Highly diastereoselective spiro-cyclopropanation of 2-arylidene-1,3-indanediones and dimethylsulfonium ylides

A highly diastereoselective spiro-cyclopropanation reaction of 2-arylidene-1,3-indanediones and dimethylsulfonium ylides has been developedviabase-induced annulation. This efficient and simple protocol features simple operations, mild conditions and excellent functional group compatibility. A variety of structurally interesting spiro-cyclopropanes were prepared in excellent yields and diastereomeric ratios (up to 97% yield and 20?:?1 dr). Also, ring expansion of the cyclopropanation product to quickly deliver a complex indeno[1,2-c]pyridazine structure showcased an interesting application of this method.

Enantioselective Oxidative Cyclization/Mannich Addition Enabled by Gold(I)/Chiral Phosphoric Acid Cooperative Catalysis

An enantioselective Mannich-type reaction of 3-butynol and nitrones is described, which affords dihydrofuran-3-ones in good yields and with excellent enantioselectivities. The reaction is initiated by gold-catalyzed alkyne oxidation and modification of the resulting gold carbene species with a tethered hydroxy group to form enolate species; the reaction terminates with an enantioselective Mannich-type addition with the assistance of chiral phosphoric acid (CPA) and hydrogen bonding. This novel pattern of alkyne transformation involving chemical bond cleavage, and a fragment modification and reassembly process, provides an atom- and step-economic method, and is the first example of cooperative asymmetric catalysis in gold-catalyzed alkyne oxidations via an α-oxo gold carbene route.