75327-39-8

Upstream product

• 35582-71-9 3-(3,4-dimethoxyphenyl)-3-(4-methoxyphenyl)propionic acid 
• 75327-40-1 2-[(3,4-Dimethoxy-phenyl)-(4-methoxy-phenyl)-methyl]-malonic acid dimethyl ester 
• 75327-41-2 2-[(3,4-Dimethoxy-phenyl)-(4-methoxy-phenyl)-methyl]-malonic acid 

Downstream Products

• 1096432-90-4 2-(3,4-dimethoxyphenyl)-2-(4-methoxyphenyl)-N-methylethanamine 
• 75327-45-6 N-methyl-3,4-dihydro-6,7-dimethoxy-4-(4-methoxyphenyl)-1-(2H)-isoquinolone 
• 75327-46-7 cherylline lactam 
• 26996-80-5 4-(4-hydroxyphenyl)-7-hydroxy-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline 
• 122480-75-5 6,7-dimethoxy-4-(4-methoxyphenyl)-1,2,3,4-tetrahydroisoquinol-1-one 

Relevant academic research and scientific papers

A short synthesis of (±)-cherylline dimethyl ether

A synthesis of (±)-cherylline dimethyl ether is reported. The key steps involved are Michael-type addition, radical azidonation of an aldehyde, Curtius rearrangement, and reduction of an isocyanate intermediate followed by Pictet-Spengler cyclization.

Synthesis of Amaryllidaceae Alkaloids, (+/-)-Cherylline and (+/-)-Latifine

Synthesis of the alkaloids, (+/-)-cherylline (1) and (+/-)-latifine (2), was accomplished by application of an isocyanate cyclization reaction according to Tsuda's two step procedure for constructing 1,2,3,4-tetrahydroisoquinol-1-one and a regioselective