75327-46-7

Upstream product

• 75327-45-6 N-methyl-3,4-dihydro-6,7-dimethoxy-4-(4-methoxyphenyl)-1-(2H)-isoquinolone 
• 4821-94-7 4,5-dimethoxyphthalic anhydride 
• 35582-71-9 3-(3,4-dimethoxyphenyl)-3-(4-methoxyphenyl)propionic acid 
• 122480-75-5 6,7-dimethoxy-4-(4-methoxyphenyl)-1,2,3,4-tetrahydroisoquinol-1-one 
• 75327-40-1 2-[(3,4-Dimethoxy-phenyl)-(4-methoxy-phenyl)-methyl]-malonic acid dimethyl ester 
• 75327-41-2 2-[(3,4-Dimethoxy-phenyl)-(4-methoxy-phenyl)-methyl]-malonic acid 
• 75327-39-8 4-[2-Isocyanato-1-(4-methoxy-phenyl)-ethyl]-1,2-dimethoxy-benzene 
• 178211-34-2 N-(Diphenyl-phosphinoylmethyl)-4,5-dimethoxy-2-(4-methoxy-benzoyl)-N-methyl-benzamide 
• 110841-23-1 6,7-dimethoxy-4-(4-methoxyphenyl)-2-methyl-2H-isoquinolin-1-one 
• 100-66-3 methoxybenzene 
• 6683-57-4 4,5-Dimethoxy-2-(4-methoxy-benzoyl)-benzoic acid 

Downstream Products

• 26996-80-5 4-(4-hydroxyphenyl)-7-hydroxy-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline 

Relevant academic research and scientific papers

Base-induced cyclization of trimethoxy-o-aroyldiphenylphosphoryl methylbenzamide: A formal synthesis of (±)Cherylline and (±)Cherylline dimethylether

The trimethoxy-o-aroyldiphenylphosphorylmethylbenzamide 9 can be cyclized by treatment with KHMDS; the procedure has been employed to synthesize (±)Cherylline 1 and its dimethylether 2.

Synthesis of Amaryllidaceae Alkaloids, (+/-)-Cherylline and (+/-)-Latifine

Synthesis of the alkaloids, (+/-)-cherylline (1) and (+/-)-latifine (2), was accomplished by application of an isocyanate cyclization reaction according to Tsuda's two step procedure for constructing 1,2,3,4-tetrahydroisoquinol-1-one and a regioselective

NEW SYNTHESIS OF ISOQUINOLINE ALKALOIDS, THALIFOLINE, CORYPALLINE, AND CHERYLLINE

Isoquinoline alkaloids, thalifoline, corypalline, and cherylline, were synthesised by application of the cyclisation reaction of β-phenyl-ethyl isocyanate to N-methylisoquinoline lactam with Magic Methyl and the regioselective cleavage reaction of aromatic methoxyl groups with methionine and methanesulphanic acid.