753456-22-3

Upstream product

• 123-76-2 levulinic acid 
• 64325-78-6 N₆-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine 
• 93134-36-2 5'-O-(4,4'-dimethoxytrityl)-N⁶-benzoyl-3'-O-levulinoyl-2'-deoxyadenosine 
• 19805-75-5 2,2,5,5-tetramethyl-3-pyrroline-3-carboxamide 

Downstream Products

• 753456-30-3 N⁶-benzoyl-5'-O-(2,2,5,5-tetramethylpyrrolidin-3-one-1-sulfinyl)-3'-O-[(N,N-diisopropylamino)(2-cyanoethyloxy)]phosphinyl-2'-deoxyadenosine 
• 753456-26-7 N⁶-benzoyl-5'-O-(2,2,5,5-tetramethylpyrrolidin-3-one-1-sulfinyl)-2'-deoxyadenosine 

Relevant academic research and scientific papers

2,2,5,5-Tetramethylpyrrolidin-3-one-1-sulfinyl group for 5′-hydroxyl protection of deoxyribonucleoside phosphoramidites in the solid-phase preparation of DNA oligonucleotides

Several nitrogen-sulfur reagents have been investigated as potential 5′-hydroxyl protecting groups for deoxyribonucleoside phosphoramidites to improve the synthesis of oligonucleotides on glass microarrays. Out of the nitrogen-sulfur-based protecting grou