753487-75-1

Upstream product

• 753487-93-3 (S)-2-{[(S)-2-((2S,3R)-2-tert-Butoxycarbonylamino-3-methoxy-3-phenyl-propionylamino)-3-methyl-butyryl]-methyl-amino}-4-methyl-pentanoic acid allyl ester 
• 63-91-2 L-phenylalanine 
• 135395-13-0 (S)-N-(tert-Butyl)-N^α-phthaloylphenylalaninamide 
• 753487-59-1 (2S,3R)-3-methoxy-N-tert-butyl-N²-phthaloylphenylalanylamide 
• 753487-55-7 (2S,3R)-N-(tert-butyloxycarbonyl)-3-methoxyphenylalanine 
• 753488-03-8 2-amino-N-tert-butyl-3-methoxy-3-phenyl-propionamide 
• 874894-76-5 (2S,3R)-2-amino-3-methoxy-3-phenylpropanoic acid 
• 32150-91-7 phthaloyl-L-phenylalanyl chloride 
• 5123-55-7 Nα-phthaloyl-L-phenylalanine 
• 160648-48-6 (2S,3R)-3-hydroxy-N-t-butyl-N^α-phthaloylphenylalaninamide 

Downstream Products

• 753487-88-6 C₈₇H₁₁₆N₈O₁₄Si 

Relevant academic research and scientific papers

Macrocyclization studies and total synthesis of cyclomarin C, an anti-inflammatory marine cyclopeptide

The studies on macrocyclization at possible sites toward the total synthesis of cyclomarin C are described. The results showed that both Trp and Phe derivatives involved in the target could not be the terminals of the final linear peptide precursors. Addi

Total synthesis of cyclomarin C

The total synthesis of cyclomarin C was accomplished through a convergent strategy from a tetrapeptide fragment and a tripeptide one. The developed methods to prepare the needed noncoded amino acids, the proper protection of peptide fragments, and identification of the optimum macrocylization site can be applied to further synthetic studies on other members of cyclomarins.