75393-93-0Relevant academic research and scientific papers
Thiourea catalyzed 1,6-conjugate addition of indoles to para-quinone methides
Wu, Guangmiao,Li, Tao,Liu, Fuhai,Zhao, Yulong,Ma, Shiqiang,Tang, Shouchu,Xie, Xingang,She, Xuegong
, (2021/09/09)
An efficient thiourea catalyzed 1,6-conjugate addition of indoles to para-quinone methides (p-QMs) was developed. p-QMs was activated by a weak hydrogen-bond effect. The reaction is featured mild reaction conditions and wide substrate scope. A series of C-3 bisaryl methine substituted indoles are prepared in high yield.
Facile construction of diverse diarylmethane scaffolds via uranyl-catalyzed 1,6-addition reaction
Yu, Jipan,Chen, Siyu,Liu, Kang,Yuan, Liyong,Zhao, Yubao,Chai, Zhifang,Mei, Lei
, (2020/06/03)
A direct 1,6-addition route of p-QMs to synthesize substituted diarylmethanes catalyzed by uranyl ion was developed. In our approach, the salient feature of this transformation is that abundant, underexploited, neglected and sequestrable depleted uranium made the reaction more sustainable. Moreover, diarylmethane derivatives were delivered in moderate to high yields with broad scope and functional group tolerance. Facile operation and mild conditions offer a practical and attractive protocol.
Synthesis of Mannich Bases of Bioactive Benzylphenols
Jurd, Leonard
, p. 81 - 83 (2007/10/02)
2,4-Bis(1,1-dimethylethyl)-6-phenol (4), prepared by oxidation of 2,4-bis(1,1-dimethylethyl)-6-phenol (1) with silver oxide in methanol, reacts with secondary amines in boiling toluene to give Manni
