75406-31-4Relevant academic research and scientific papers
Compound for preparing baloxavir or derivatives thereof as well as preparation method and application of compound
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, (2021/02/10)
The invention relates to a preparation method of a compound shown as a formula VIII for preparing baloxavir or derivatives thereof, a compound shown as a formula I for preparing the compound shown asthe formula VIII and a preparation method of the compound shown as the formula I. The compound shown as the formula I is used for preparing the compound shown as the formula VIII, the baloxavir or thederivative thereof. The preparation method is simple and convenient to operate, and the raw materials are easily available and low in cost; reaction conditions are mild, and the method is safe and environment-friendly; side reactions are few, and the product purity is high; and the quality is controllable, and the method is suitable for industrial production.
THE FACILE CONVERSION OF A β-LACTAM INTO 2,3-DIHYDRO-1,3-BENZOXA(THIA)ZIN-4-ONES
Arnoldi, Anna,Merlini, Lucio,Scaglioni, Leonardo
, p. 257 - 260 (2007/10/02)
The reaction of 4-acetoxyazetidin-2-one with esters of salicylic acid in the presence of base gives rise to an intramolecular ring transformation to 2,3-dihydro-1,3-benzoxazin-4-one-2-acetic acid and its esters.A similar reaction occurs with benzyl 2-merc
