75420-44-9Relevant articles and documents
Synthesis of 10-Aza-9-oxakalkitoxin by N-O Bond Formation
Crich, David,Upadhyaya, Kapil
supporting information, p. 1833 - 1836 (2022/03/16)
We describe a formal synthesis of 10-aza-9-oxakalkitoxin, the hydroxalog of the cytotoxic marine natural product kalkitoxin, that features Mukaiyama Markovnikov silyl peroxidation of a terminal alkene and N-O bond formation as the central enabling steps.
Total synthesis of (-)-exiguolide via an organosilane-based strategy
Li, Hongze,Xie, Hengmu,Zhang, Zhigao,Xu, Yongjin,Lu, Ji,Gao, Lu,Song, Zhenlei
supporting information, p. 8484 - 8487 (2015/05/20)
An organosilane-based strategy has been used to accomplish the convergent total synthesis of (-)-exiguolide. The key steps involve: (1) geminal bis(silyl) Prins cyclization to construct the A ring; (2) silicon-protected RCM reaction to construct the 20-me
A ring-closing metathesis approach to cyclic α,β-dehydroamino acids
Hekking, Koen F. W.,Waalboer, Dennis C. J.,Moelands, Marcel A. H.,Van Delft, Floris L.,Rutjes, Floris P. J. T.
supporting information; experimental part, p. 95 - 106 (2009/04/10)
A comprehensive study on the synthesis and ring-closing metathesis (RCM) of α,β-dehydroamino acids is described. This sequence has led to the formation of a range of biologically relevant functionalized nitrogen heterocycles. The incorporation of chiral b
