75445-46-4

Basic information

• Product Name: 2-(2-Amino-2-methylpropyl)-4-methylphenol
• Synonyms: 2-(2-Amino-2-methylpropyl)-4-methylphenol
• CAS NO: 75445-46-4
• Molecular Weight: 179.262
• Mol File: 75445-46-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2-Amino-2-methylpropyl)-4-methylphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-Amino-2-methylpropyl)-4-methylphenol(75445-46-4)
• EPA Substance Registry System: 2-(2-Amino-2-methylpropyl)-4-methylphenol(75445-46-4)

Safety Data

• Hazardous Substances Data: 75445-46-4(Hazardous Substances Data)

Upstream product

• 21236-74-8 4-methyl-2-(piperidin-1-ylmethyl)phenol 
• 4383-07-7 2-hydroxymethyl-4-methylphenol 
• 106-44-5 p-cresol 
• 7204-35-5 2-(dimethylamino-methyl)-4-methyl-phenol 
• 75445-40-8 4-Methyl-2-(2-methyl-2-nitropropyl)phenol 
• 79-46-9 2-nitropropane 

Relevant articles and documents

2-(2-Amino-2-methylpropyl)phenols by C-C-Linkage of 2-Hydroxybenzyl Alcohols with 2-Nitropropane Anions

The 2-hydroxybenzyl alcohols 1, 6, 8a, and 8e can be converted into the 2-(2-methyl-2-nitropropyl)-phenols 2, 7, and 9 by a SRN1-reaction with the sodium salt of 2-nitropropane.Catalytic hydrogenation yields the amines 3 and 10.The consequent reactions - leading to the quaternary salts 13 and 14 and as to the addition-compounds 15 and 16 - are negatively influenced by the strong steric shielding of the amino groups.