75500-00-4Relevant academic research and scientific papers
Sustainable HandaPhos-ppm Palladium Technology for Copper-Free Sonogashira Couplings in Water under Mild Conditions
Handa, Sachin,Smith, Justin D.,Zhang, Yitao,Takale, Balaram S.,Gallou, Fabrice,Lipshutz, Bruce H.
, p. 542 - 545 (2018)
Complexation of ca. 1000 ppm Pd(OAc)2 with the ligand HandaPhos (1-1.5:1) leads to a precatalyst that efficiently mediates Sonogashira couplings in aqueous nanomicelles under very mild conditions. Neither copper nor organic solvent is required
A new synthesis of n-blocked dihydrouracil and dihydroorotic acid derivatives using lithium tri-sec-butyl borohydride as reducing agent
Hannon, Stephen J.,Kundu, Nitya G.,Hertzberg, Robert P.,Bhatt, Ram S.,Heidelberger, Charles
, p. 1105 - 1108 (2007/10/02)
1,3-Di-N-substituted uracil and its derivatives have been reduced with lithium-tri-sec-butyl borohydride to the corresponding 5,6-dihydro compounds in excellent yields. Alkylation of 5-position of uracil is also very conveniently accomplished.
