75640-87-8Relevant articles and documents
Enhancing the enantioselective recognition and sensing of chiral anions by halogen bonding
Lim, Jason Y. C.,Marques, Igor,Ferreira, Liliana,Félix, Vítor,Beer, Paul D.
, p. 5527 - 5530 (2016)
Chiral halogen bonding (S)-BINOL-based receptors are demonstrated to enhance the enantioselective recognition and sensing of chiral anions compared to their hydrogen bonding analogues. Computational studies attribute this behaviour to the strict linearity of halogen bonding (XB) and steric environment conferred by the XB donor groups bridged by the (S)-BINOL motif.
A Chiral, Dendralenic C-H Acid
H?fler, Denis,List, Benjamin
supporting information, p. 38 - 39 (2021/12/29)
We report the synthesis of a chiral dendralenic C H acid, which contains three unsubstituted binaphthyl moieties. This motif and an achiral variant can be made from their corresponding bis(sulfone) precursors in one step. Despite the presence of the enantiopure binaphthyl backbone, the newly designed chiral C H acid showed only poor enantioselectivity in a Mukaiyama aldol reaction. First attempts toward the synthesis of 3,3'-hexasubstituted binaphthyl-based dendralenic acids are also reported.
Enantioselective Ni-Catalyzed Electrochemical Synthesis of Biaryl Atropisomers
Chen, Song,Chen, Yue-Gang,Gao, Pei-Sen,Liu, Dong,Ma, Hong-Xing,Mei, Tian-Sheng,Qiu, Hui,Shuai, Bin,Wang, Yun-Zhao
supporting information, p. 9872 - 9878 (2020/06/27)
A scalable enantioselective nickel-catalyzed electrochemical reductive homocoupling of aryl bromides has been developed, affording enantioenriched axially chiral biaryls in good yield under mild conditions using electricity as a reductant in an undivided cell. Common metal reductants such as Mn or Zn powder resulted in significantly lower yields in the absence of electric current under otherwise identical conditions, underscoring the enhanced reactivity provided by the combination of transition metal catalysis and electrochemistry.
Synthesis of Chiral 3,3?-Disubstituted (S)-BINOL Derivatives via the Kumada and Suzuki Coupling and Their Antibacterial Activity
Ankireddy, A. Reddy,Paidikondala,Syed,Gundla,Reddy, Ch. Venkata Ramana,Ganapathi
, p. 1507 - 1517 (2020/09/21)
Abstract: A new series of 3,3?-disubstituted chiral (S)-BINOL derivatives 6a–6k has been synthesized viathe Kumada and Suzuki–Miyaura coupling reactions using (S)-BINOL as the initial compound. The Kumada coupling has beenfound to be superior in terms of