13101-92-3

Basic information

• Product Name: Naphthalene, 1-chloro-2-Methoxy-
• Synonyms: Naphthalene, 1-chloro-2-Methoxy-;1-Chloro-2-Methoxynaphthalene
• CAS NO: 13101-92-3
• Molecular Formula: C₁₁H₉ClO
• Molecular Weight: 192.64156
• Mol File: 13101-92-3.mol
• Article Data: 28

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Naphthalene, 1-chloro-2-Methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Naphthalene, 1-chloro-2-Methoxy-(13101-92-3)
• EPA Substance Registry System: Naphthalene, 1-chloro-2-Methoxy-(13101-92-3)

Safety Data

• Hazardous Substances Data: 13101-92-3(Hazardous Substances Data)

Usage

General Description

1-Chloro-2-methoxynaphthalene, also known as 2-Methoxy-1-chloronaphthalene, is a chemical compound with the molecular formula C11H9ClO. It belongs to the family of Naphthalenes, which are polycyclic aromatic compounds that contain two fused benzene rings. This particular compound is slightly soluble in water but will readily dissolve in many organic solvents such as ethanol, toluene, and diethyl ether. The physical appearance of 1-Chloro-2-methoxynaphthalene is typically a light yellow liquid, and it has a distinctive aromatic odor. Naphthalene, 1-chloro-2-methoxy- finds applications in the chemical industry as an intermediate in the synthesis of other compounds. It is advised to handle this compound with caution as it can potentially cause skin, eye, and respiratory irritation.

Upstream product

• 118-52-5 1,3-dichloro-5,5-dimethylhydantoin 
• 93-04-9 2-Methoxynaphthalene 
• 633-99-8 1-chloro-2-naphthol 
• 77-78-1 dimethyl sulfate 
• 79-46-9 2-nitropropane 
• 5392-12-1 2-methoxy-1-naphthaldehyde 
• 13343-92-5 methyl ester of 2-methoxy-1-naphthalenecarboxylic acid 
• 947-62-6 2-methoxy-1-naphthoic acid 
• 2283-08-1 2-hydroxy-1-naphthalenecarboxylic acid 
• 3401-47-6 1-bromo-2-methoxynaphthalene 
• 135-19-3 β-naphthol 
• 10026-13-8 phosphorus pentachloride 
• 79-24-3 Nitroethane 
• 628-13-7 pyridine hydrochloride 

Downstream Products

• 633-99-8 1-chloro-2-naphthol 
• 2246-42-6 2-methoxynaphthylamine 
• 1021176-79-3 1-mesityl-2'-methoxynaphthalene 
• 1200804-92-7 3-(4-benzyl-5,6-dihydropyridin-1(2H)-yl)-1-(5-chloro-6-methoxynaphthalen-2-yl)propan-1-ol 
• 1200804-66-5 4-benzyl-1-(3-(5-chloro-6-methoxynaphthalen-2-yl)-3-hydroxypropyl)piperidin-4-ol 
• 1394148-08-3 3-(4-benzyl-5,6-dihydropyridin-1(2H)-yl)-1-(5-chloro-6-methoxynaphthalen-2-yl)propan-1-one hydrochloride 
• 1394148-10-7 3-(4-benzyl-4-hydroxypiperidin-1-yl)-1-(5-chloro-6-methoxynaphthalen-2-yl)propan-1-one hydrochloride 
• 1394148-20-9 2-(4-benzyl-4-hydroxypiperidin-1-yl)-1-(5-chloro-6-methoxynaphthalen-2-yl)propan-1-one hydrochloride 
• 1200805-56-6 3-(4-benzyl-5,6-dihydropyridin-1(2H)-yl)-1-(5-chloro-6-methoxynaphthalen-2-yl)propan-1-ol hydrochloride 
• 1200805-30-6 4-benzyl-1-(3-(5-chloro-6-methoxynaphthalen-2-yl)-3-hydroxypropyl)piperidin-4-ol hydrochloride 
• 1200806-01-4 3-(4-benzyl-5,6-dihydropyridin-1(2H)-yl)-1-(5-chloro-6-methoxynaphthalen-2-yl)propan-1-one 
• 1331780-88-1 3-(4-benzyl-4-hydroxypiperidin-1-yl)-1-(5-chloro-6-methoxynaphthalen-2-yl)propan-1-one 
• 1200805-84-0 2-(4-benzyl-4-hydroxypiperidin-1-yl)-1-(5-chloro-6-methoxynaphthalen-2-yl)propan-1-one 
• 35294-28-1 (R)-2,2'-dimethoxy-1,1'-dinaphthyl 

Relevant articles and documents

Decarbonylative halogenation by a vanadium complex

Metal-catalyzed halogenation of the C-H bond and decarbonylation of aldehyde are conventionally done in nature. However, metal-mediated decarbonylative halogenation is unknown. We have developed the first metal-mediated decarbonylative halogenation reaction starting from the divanadium oxoperoxo complex K3V5+2(O 22-)4(O2-)2(μ-OH) (1). A concerted decarbonylative halogenation reaction was proposed based on experimental observations.

Efficient halogenation synthesis method of aryl halide

The invention discloses an efficient halogenation synthesis method of aryl halide. The method comprises the following step: in the presence of a catalyst (sulfoxide or oxynitride), a halogenation reagent and a solvent, carrying out a halogenation reaction on an aromatic ring compound to obtain the aryl halide. According to the present invention, in the presence of a catalyst (sulfoxide or nitrogenoxide), a halogenation reagent and a solvent, the aromatic ring is subjected to an efficient halogenation reaction, such that the very useful aryl halide can be obtained with high activity and high selectivity; and by adopting the method disclosed by the invention, aryl halides can be efficiently synthesized, and the method has a wide application prospect in actual production.

Oxidative Photochlorination of Electron-Rich Arenes via in situ Bromination

Electron-rich arenes are oxidatively photochlorinated in the presence of catalytic amounts of bromide ions, visible light, and 4CzIPN as organic photoredox catalyst. The substrates are brominated in situ in a first photoredox-catalyzed oxidation step, followed by a photocatalyzed ipso-chlorination, yielding the target compounds in high ortho/para regioselectivity. Dioxygen serves as a green and convenient terminal oxidant. The use of aqueous hydrochloric acid as the chloride source reduces the amount of saline by-products.