756487-18-0 Usage
Uses
Used in Medicinal Chemistry:
[(S)-5-(S)-2-[6-(2,5-Dioxo-2,5-dihydro-pyrrol-1-yl)-hexanoylamino]-3-phenyl-propionylamino-5-(4-hydroxymethyl-phenylcarbamoyl)-pentyl]-carbamic acid tert-butyl ester is used as a compound with potential applications in medicinal chemistry due to its intricate structure and the presence of various functional groups that may contribute to its biological activity.
Used in Biochemistry:
In Biochemistry, [(S)-5-(S)-2-[6-(2,5-Dioxo-2,5-dihydro-pyrrol-1-yl)-hexanoylamino]-3-phenyl-propionylamino-5-(4-hydroxymethyl-phenylcarbamoyl)-pentyl]-carbamic acid tert-butyl ester is used as a subject for research to understand the interactions and reactivity of its different functional groups with biological systems.
Used in Pharmaceutical Research:
Within the Pharmaceutical Research industry, [(S)-5-(S)-2-[6-(2,5-Dioxo-2,5-dihydro-pyrrol-1-yl)-hexanoylamino]-3-phenyl-propionylamino-5-(4-hydroxymethyl-phenylcarbamoyl)-pentyl]-carbamic acid tert-butyl ester is used as a candidate compound for the development of new drugs, given its complex structure and potential for biological activity.
Used in Organic Chemistry:
In Organic Chemistry, [(S)-5-(S)-2-[6-(2,5-Dioxo-2,5-dihydro-pyrrol-1-yl)-hexanoylamino]-3-phenyl-propionylamino-5-(4-hydroxymethyl-phenylcarbamoyl)-pentyl]-carbamic acid tert-butyl ester is used as a model compound to study the synthesis and characterization of similar chemical groups, providing insights into their reactivity and properties.
Check Digit Verification of cas no
The CAS Registry Mumber 756487-18-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,5,6,4,8 and 7 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 756487-18:
(8*7)+(7*5)+(6*6)+(5*4)+(4*8)+(3*7)+(2*1)+(1*8)=210
210 % 10 = 0
So 756487-18-0 is a valid CAS Registry Number.
756487-18-0Relevant academic research and scientific papers
Monoclonal antibody mediated intracellular targeting of tallysomycin S 10b
Walker, Michael A.,King, H. Dalton,Dalterio, Richard A.,Trail, Pamela,Firestone, Raymond,Dubowchik, Gene M.
, p. 4323 - 4327 (2007/10/03)
The potency of tallysomycin S10b (TLM S10b) an analogue bleomycin was enhanced by up to 875-fold when it was conjugated to the internalizing antibody BR96. Attachment to the antibody is achieved via a Cathepsin B cleavable linker. The enhancement in potency is believed to be a result of cellular uptake of the conjugate upon antigen binding followed by rapid release of the drug inside the lysosome. This method provides a novel approach for increasing the potency and therapeutic index of nominally moderately-active cytotoxic agents.
