756494-08-3Relevant academic research and scientific papers
SNAr displacements with 6-(fluoro, chloro, bromo, iodo, and alkylsulfonyl)purine nucleosides: Synthesis, kinetics, and mechanism
Liu, Jiangqiong,Robins, Morris J.
, p. 5962 - 5968 (2008/02/12)
SNAr reactions with 6-(fluoro, chloro, bromo, iodo, and alkylsulfonyl)purine nucleosides and nitrogen, oxygen, and sulfur nucleophiles were studied. Pseudo-first-order kinetics were measured with 6-halopurine compounds, and comparative reactivi
SNAr iodination of 6-chloropurine nucleosides: Aromatic finkelstein reactions at temperatures below -40°C1
Liu, Jiangqiong,Janeba, Zlatko,Robins, Morris J.
, p. 2917 - 2919 (2007/10/03)
(Equation Presented) Mesitoyl or toluoyl esters of inosine and 2′-deoxyinosine were deoxychlorinated at C6 to give the crystalline 6-chloropurine nucleoside derivatives, which underwent quantitative conversion to the 6-iodo analogues with Nal/TFA/butanone
