75652-74-3 Usage
General Description
"(3Z,5S)-3-(1-Hydroxyethylidene)-5-[(S)-1-methylpropyl]-2,4-pyrrolidinedione" is a chemical compound with the molecular formula C11H17NO3. It belongs to the class of pyrrolidinediones and is a derivative of the amino acid proline. (3Z,5S)-3-(1-Hydroxyethylidene)-5-[(S)-1-methylpropyl]-2,4-pyrrolidinedione is a chiral molecule, meaning it has different spatial arrangements of atoms that are non-superimposable mirror images of each other. It is commonly used in organic synthesis and pharmaceutical research due to its unique structure and potential biological activity. The stereochemistry of this compound, indicated by the (3Z,5S) designation, further emphasizes its importance in medicinal chemistry and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 75652-74-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,6,5 and 2 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 75652-74:
(7*7)+(6*5)+(5*6)+(4*5)+(3*2)+(2*7)+(1*4)=153
153 % 10 = 3
So 75652-74-3 is a valid CAS Registry Number.
75652-74-3Relevant articles and documents
Further Reactions of t-Butyl 3-Oxobutanthioate and t-Butyl 4-Diethylphosphono-3-oxobutanthioate: Carbonyl Coupling Reactions, Amination, Use in The Preparation of 3-Acyltetramic Acids and Application to The Total Synthesis of Fuligorubin A.
Ley, Steven V.,Smith, Stephen C.,Woodward, Peter R.
, p. 1145 - 1174 (2007/10/02)
Key words: Acyltetramic acid; Phosphonate; Wadsworth-Emmons; Dieckmann cyclisation; Fuligorubin A. Abstract: The use of t-butyl-3-oxobutanthioate (1) and t-butyl 4-diethylphosphono-3-oxobuthanthioate (2) for the preparation of homologated derivatives suitable for amination in the presence of silver(I) trifluoroacetate to afford the corresponding β-ketoamides is discussed.In particular Wadsworth-Emmons coupling reactions of (2) with various carbonyl compounds gave good yields of E-substituted products.Many of the β-ketoamides were shown to be suitable precursors for 3-acyltetramic acids using a Dieckman cyclisation with tetra-n-butyl ammonium fluoride as the cyclising base.These new reactions were applied to the total synthesis of the polyene 3-acyltetramic acid fuligorubin A.
