75681-84-4Relevant academic research and scientific papers
Reaction de CF2=CH2 avec les organolithiens . Une nouvelle preparation du difluorovinyllithium
Sauvetre, R.,Normant, J. F.
, p. 957 - 958 (2007/10/02)
2,2-Difluorovinyllithium has been prepared in quantitative yield from CF2=CH2 and sec.butyllithium at low temperature.Reaction of 2,2-difluorovinyllithium with carbonyl groups gives the corresponding alcohols.
Durch Bromirung ausgeloeste Umlagerung tertiaerer Allylalkohole: Der Einfluss eines Fluor-Substituent auf Reactionsgeschwindigkeit und reactionsverlauf
Nagakura, Isao,Savary, Dang Ngoc-Hue,Schlosser, Manfred
, p. 1257 - 1263 (2007/10/02)
The allyl alcohol bearing a methyl and a t-butyl group at the hydroxylated position was found to undergo a rearrangement when treated with bromine (or N-bromosuccinimide) in an aqueous medium and to afford a product mixture containing two regioisomeric ketones and one oxirane.Introduction of an additional methyl group or a fluorine atom at the non-terminal olefinic center led to a more selective discrimination between potential migratory groups.As the result of an exclusive t-butyl shift only one product, a ketone, was formed in both cases.Whereas the reaction rate only was slightly affected by the additional methyl group, it was substantually decreased by the fluorine atom.
