7569-62-2

Basic information

• Product Name: (5-CHLORO-2-METHOXYPHENYL)ACETIC ACID
• Synonyms: 2-(Carboxymethyl)-4-chloroanisole;5-chloro-2-methoxyBenzeneacetic acid
• CAS NO: 7569-62-2
• Molecular Formula: C₉H₉ClO₃
• Molecular Weight: 200.619
• Mol File: 7569-62-2.mol

Chemical Properties

• Boiling Point: 323.5°Cat760mmHg
• Flash Point: 149.4°C
• Appearance: /
• Density: 1.312g/cm³
• Vapor Pressure: 0.000107mmHg at 25°C
• Refractive Index: 1.553
• CAS DataBase Reference: (5-CHLORO-2-METHOXYPHENYL)ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (5-CHLORO-2-METHOXYPHENYL)ACETIC ACID(7569-62-2)
• EPA Substance Registry System: (5-CHLORO-2-METHOXYPHENYL)ACETIC ACID(7569-62-2)

Safety Data

• Hazardous Substances Data: 7569-62-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(5-CHLORO-2-METHOXYPHENYL)ACETIC ACID is used as an analgesic and anti-inflammatory agent for managing pain and inflammation in conditions such as rheumatoid arthritis and osteoarthritis. It is effective in reducing the symptoms by inhibiting the production of prostaglandins, which are responsible for pain and inflammation.
Used in Pain Management:
(5-CHLORO-2-METHOXYPHENYL)ACETIC ACID is used as a pain reliever to provide relief from acute and chronic pain conditions. Its analgesic properties make it a suitable option for patients experiencing moderate to severe pain.
Used in Anti-pyretic Applications:
(5-CHLORO-2-METHOXYPHENYL)ACETIC ACID is used as an anti-pyretic to reduce fever and associated symptoms. Its ability to lower body temperature makes it a useful medication for managing feverish conditions.

InChI:InChI=1/C9H9ClO3/c1-13-8-3-2-7(10)4-6(8)5-9(11)12/h2-4H,5H2,1H3,(H,11,12)

Upstream product

• 917107-30-3 2-(5-chloro-2-methoxy-phenyl)-1-morpholin-4-yl-ethanethione 
• 93-25-4 2-methoxyphenylacetic acid 
• 26939-01-5 5-chloro-2-methoxyphenylacetic acid,methyl ester 
• 7035-11-2 4-chloro-2-chloromethyl-1-methoxy-benzene 
• 623-12-1 4-chloromethoxybenzene 
• 6342-64-9 2-methoxy-5-chloroacetophenone 
• 7048-38-6 (5-chloro-2-methoxy-phenyl)-acetonitrile 

Downstream Products

• 7569-63-3 (5-chloro-2-methoxyphenyl)acetyl chloride 
• 7569-69-9 (2-Methoxy-5-chlor-phenyl)-aethanol 
• 26939-01-5 5-chloro-2-methoxyphenylacetic acid,methyl ester 
• 76322-41-3 ethyl (5-chloro-2-hydroxyphenyl)acetate 
• 1050481-78-1 ethyl 2-(5-chloro-2-methoxyphenyl)acetate 
• 917107-29-0 2-(5-chloro-2-hydroxyphenyl)-N-methylacetamide 
• 913650-07-4 2-[5-chloro-2-(methyloxy)phenyl]acetamide 

Relevant articles and documents

Efficient halogenation synthesis method of aryl halide

The invention discloses an efficient halogenation synthesis method of aryl halide. The method comprises the following step: in the presence of a catalyst (sulfoxide or oxynitride), a halogenation reagent and a solvent, carrying out a halogenation reaction on an aromatic ring compound to obtain the aryl halide. According to the present invention, in the presence of a catalyst (sulfoxide or nitrogenoxide), a halogenation reagent and a solvent, the aromatic ring is subjected to an efficient halogenation reaction, such that the very useful aryl halide can be obtained with high activity and high selectivity; and by adopting the method disclosed by the invention, aryl halides can be efficiently synthesized, and the method has a wide application prospect in actual production.

MAXI-K POTASSIUM CHANNEL OPENERS FOR THE TREATMENT OF FRAGILE X ASSOCIATED DISORDERS

The present invention relates to the compounds of formula (I) and pharmaceutical compositions containing these compounds. The compounds provided herein can act as maxi-K potassium channel openers, which makes them suitable for use in therapy, particularly in the treatment or prevention of fragile X associated disorders, such as fragile X syndrome.

Novel 1,4-benzothiazine derivatives as large conductance Ca 2+-activated potassium channel openers

The design and synthesis of a novel class of 1,4-benzothiazines targeted for the large-conductance calcium-activated potassium channels (BK) are presented. In vitro functional characterization of BK channel opening activity was assessed by measuring the r

Piperazinyl CCR1 antagonists-optimization of human liver microsome stability

The synthesis, biological activity, and pharmacokinetic profile of CCR1 antagonists are described.

N-AMIDE DERIVATIVES OF 8-AZABICYCLO[3.2.1]OCT-3-YL AS CCR1 ANTAGONISTS

The present invention relates to new antagonists of the interaction between the CCR1 Chemokine receptor and its ligands, including MIP-1α (CCL3), in particular new N-amide derivatives of 8-azabicyclo[3.2.1]oct-3-yl of formula (I).

PREPARATION OF 3-FLUORO OXINDOLE DERIVATIVES

The present invention relates to novel itermediates of formula (1) wherein the wavy bond ( SIMILAR SIMILAR ) represents the racemate, the (R)-enantiomer or the (S)-enantiomer; and R is hydrogen, a carboxyl-protecting group or a cation of an addition salt;

Methods of using piperazine derivatives

The present invention relates to compounds of the formula I and the pharmaceutically acceptable forms thereof; wherein X, Y, a, b, c, d, R1, R2, R3, R4 and R5 are as defined herein. Moreover, the present invention is also directed at pharmaceutical compositions comprising a compound of the formula I and a pharmaceutically acceptable carrier. Furthermore, the present invention is directed at methods of using the herein described compounds and compositions for treating or preventing a disorder or condition that can be treated or prevented by antagonizing the CCR1 receptor in a mammal.

PIPERIDINE DERIVATIVES AND THEIR USE AS SELECTIVE INHIBITORS OF MIP-1ALPHA BINDING TO ITS RECEPTOR CCR1

A compound of the formula (I) wherein a, b, c R1, R2, R3, R4, R5, R6, R7, Q, W, Y, and Z are defined as above , useful as potent and selective inhibitors of MIP-1α (CCL3) binding to its receptor CCR1 found on inflammatory and immunomodulatory cells (preferably leukocytes and lymphocytes).

Novel sulfonic acid derivatives

A compound of the formula or the pharmaceutically acceptable salt thereof; wherein X, Y, a, b, c, d, R1, R2, R3 and R5 are as defined above useful to treat inflammation and other immune disorders.