7571-57-5

Upstream product

• 2357-52-0 3-fluoro-4-methoxyphenyl bromide 
• 530-62-1 1,1'-carbonyldiimidazole 
• 321-28-8 1-fluoro-2-methoxybenzene 
• 390-67-0 1,1-bis-(3-fluoro-4-methoxy-phenyl)-propene 

Downstream Products

• 345-67-5 3,3'-difluoro-4,4'-dihydroxy-benzophenone 
• 342-74-5 1,1-bis-(3-fluoro-4-methoxy-phenyl)-2-phenyl-ethene 
• 447-19-8 3,3'-dibromo-5,5'-difluoro-4,4'-dihydroxy-benzophenone 
• 395-08-4 4,4'-diethoxy-3,3'-difluoro-benzophenone 
• 441-52-1 1,1-bis-(4-ethoxy-3-fluoro-phenyl)-2-phenyl-ethene 
• 386-85-6 1-chloro-2,2-bis-(3-fluoro-4-methoxy-phenyl)-1-phenyl-ethene 
• 436-97-5 1-bromo-2,2-bis-(3-fluoro-4-methoxy-phenyl)-1-phenyl-ethene 

Relevant academic research and scientific papers

Divergent Synthesis of Trifluoromethyl Sulfoxides and β-SCF3Carbonyl Compounds by Tandem Trifluoromethylthiolation/Rearrangement of Allylic and Propargylic Alcohols

A selenium-catalyzed trifluoromethylthiolation/[2,3]-sigmatropic rearrangement of tertiary allylic and propargylic alcohols which could provide straightforward and facile access to trifluoromethyl sulfoxides was developed. Various allylic and allenic trifluoromethyl sulfoxides were obtained with moderate to excellent yields. Meanwhile, a Lewis acid mediated trifluoromethylthiolation/1,2-rearrangement to synthesize β-SCF3 carbonyl compounds was also accomplished. These two tandem reactions feature with mild reaction conditions and metal-free. During these two reactions, the chemoselectivity of electrophilic trifluoromethylthiolation was revealed.