757155-82-1Relevant academic research and scientific papers
A novel heterocyclic compound improves working memory in the radial arm maze and modulates the dopamine receptor D1R in frontal cortex of the Sprague-Dawley rat
Hussein, Ahmed M.,Aher, Yogesh D.,Kalaba, Predrag,Aher, Nilima Y.,Draga?evi?, Vladimir,Radoman, Bojana,Ili?, Marija,Leban, Johann,Beryozkina, Tetyana,Ahmed, Abdel Baset M.A.,Urban, Ernst,Langer, Thierry,Lubec, Gert
, p. 308 - 315 (2017)
A series of compounds have been shown to enhance cognitive function via the dopaminergic system and indeed the search for more active and less toxic compounds is continuing. It was therefore the aim of the study to synthetise and test a novel heterocyclic
Structure-Activity Relationships of Novel Thiazole-Based Modafinil Analogues Acting at Monoamine Transporters
Kalaba, Predrag,Ili?, Marija,Aher, Nilima Y.,Draga?evi?, Vladimir,Wieder, Marcus,Zehl, Martin,Wackerlig, Judith,Beyl, Stanislav,Sartori, Simone B.,Ebner, Karl,Roller, Alexander,Lukic, Natalie,Beryozkina, Tetyana,Gonzalez, Eduardo Rene Perez,Neill, Philip,Khan, Jawad Akbar,Bakulev, Vasiliy,Leban, Johann Jakob,Hering, Steffen,Pifl, Christian,Singewald, Nicolas,Lubec, Jana,Urban, Ernst,Sitte, Harald H.,Langer, Thierry,Lubec, Gert
, p. 391 - 417 (2020/02/20)
Atypical dopamine reuptake inhibitors, such as modafinil, are used for the treatment of sleeping disorders and investigated as potential therapeutics against cocaine addiction and for cognitive enhancement. Our continuous effort to find modafinil analogue
HETEROCYCLIC COMPOUNDS WITH WORKING MEMORY ENHANCING ACTIVITY
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Page/Page column 41, (2016/02/29)
The present invention relates to a chemical compound having the general formula (I): wherein R1 and R2 are, equal or independently, aryl, heteroaryl; wherein RTA is a 2-1,3-, or 4- 1,3- or 5-1,3-thiazole ring and its use in for improving; the short term memory and/or the working memory.
MODULATORS OF CXCR7
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Page/Page column 65, (2010/06/11)
Compounds having formula (I) or pharmaceutically acceptable salts, hydrates or N-oxides thereof are provided and are useful for binding to CXCR7, and treating diseases that are dependent, at least in part, on CXCR7 activity. Accordingly, the present inven
