757190-01-5

Upstream product

• 757189-93-8 (2S)-N-[4,5-dimethoxy-2-nitrobenzoyl]-4-(methoxycarbonylmethylidene)-pyrrolidine-2-carboxaldehyde diethyl thioacetal 
• 757189-94-9 (2S)-N-[4,5-dimethoxy-2-nitrobenzoyl]-4-(carboxymethylidene)-pyrrolidine-2-carboxaldehyde diethyl thioacetal 
• 757189-84-7 methyl 4-(N-t-butoxycarbonyl)aminoethoxy-5-methoxy-2-nitrobenzoate 
• 757189-86-9 4-(N-t-butoxycarbonyl)aminoethoxy-5-methoxy-2-nitrobenzoic acid 
• 745014-24-8 (2S)-N-[4-(N-t-butoxycarbonyl)aminoethoxy-5-methoxy-2-nitrobenzoyl]pyrrolidine-2-carboxaldehyde diethyl thioacetal 
• 175733-04-7 (2S)-N-[4-(2-aminoethoxy)-5-methoxy-2-nitrobenzoyl]pyrrolidine-2-carboxaldehyde diethyl thioacetal 
• 625123-46-8 methyl (2S,4R)-N-[4-benzyloxy-5-methoxy-2-nitrobenzoyl]-4-(t-butyldimethylsilyl)-oxypyrrolidine-2-carboxylate 
• 625123-47-9 (2S,4R)-N-[4-benzyloxy-5-methoxy-2-nitrobenzoyl]-4-(t-butyldimethylsilyl)-oxypyrrolidine-2-carboxaldehyde 
• 625123-48-0 (2S,4R)-N-[4-benzyloxy-5-methoxy-2-nitrobenzoyl]-4-hydroxypyrrolidine-2-carboxaldehyde diethyl thioacetal 
• 27883-60-9 4-hydroxy-5-methoxy-2-nitrobenzoic acid methyl ester 
• 61032-41-5 methyl 4-(benzyloxy)-5-methoxy-2-nitrobenzoate 
• 64154-78-5 4-benzyloxy-5-methoxy-2-nitrobenzoyl chloride 
• 60547-92-4 4-(benzyloxy)-5-methoxy-2-nitrobenzoic acid 
• 757189-97-2 (2S)-N-{4-[(2S)-N-(4,5-dimethoxy-2-nitrobenzoyl)-pyrrolidine-2-carboxaldehyde diethyl thioacetal-4-(carboxamidomethylidene)-N-ethyl]oxy-5-methoxy-2-nitrobenzoyl}pyrrolidine-2-carboxaldehyde diethyl thioacetal 

Relevant academic research and scientific papers

Synthesis and DNA binding affinity of novel A-C8/C-C2-exo unsaturated alkoxyamido-linked pyrrolo[2,1-c][1,4]benzodiazepine dimers.

The synthesis of novel A-C8/C-C2-exo unsaturated alkoxyamido-linked pyrrolo[2,1-c][1,4]benzodiazepine dimers is reported and these dimers show significant DNA binding affinity and they also exhibit moderate anticancer activity.