75732-41-1

Basic information

• Product Name: Silanol, (1,1-dimethylethyl)dimethyl-, benzoate
• Synonyms: Dimethyl-tert-butylsilyl benzoate
• CAS NO: 75732-41-1
• Molecular Formula: C13H20O2Si
• Molecular Weight: 236.386
• Mol File: 75732-41-1.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Silanol, (1,1-dimethylethyl)dimethyl-, benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Silanol, (1,1-dimethylethyl)dimethyl-, benzoate(75732-41-1)
• EPA Substance Registry System: Silanol, (1,1-dimethylethyl)dimethyl-, benzoate(75732-41-1)

Safety Data

• Hazardous Substances Data: 75732-41-1(Hazardous Substances Data)

Upstream product

• 41879-37-2 t-butyldimethylsilyl amine 
• 65-85-0 benzoic acid 
• 79185-06-1 t-butyldimethyl((4-phenylbut-1-en-2-yl)oxy)silane 
• 93-97-0 benzoic acid anhydride 
• 87258-11-5 2-(tert-Butyl-dimethyl-silanyloxy)-4-phenyl-but-2-yl-hydroperoxide 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 29681-57-0 tert-butyldimethylsilane 
• 74472-22-3 allyl tert-butyldimethylsilane 
• 54925-64-3 N-(tert-butyldimethylsilyl)imidazole 
• 92912-32-8 α-cyclopropyl-α-dimethyl-t-butylsilyloxy-ethyl peroxybenzoate 
• 2078-12-8 trimethylsilyl benzoate 
• 77086-38-5 ketene t-butyldimethylsilyl methyl acetal 
• 93241-11-3 Benzenecarboperoxoic acid 1-(tert-butyl-dimethyl-silanyloxy)-1-methyl-ethyl ester 
• 87258-14-8 Benzenecarboperoxoic acid 1-(tert-butyl-dimethyl-silanyloxy)-1-methyl-3-phenyl-propyl ester 

Downstream Products

• 65-85-0 benzoic acid 
• 532-55-8 Benzoyl isothiocyanate 
• 618-32-6 Benzoyl bromide 
• 66324-10-5 tert-butyldimethyl(1-phenylvinyloxy)silane 

Relevant articles and documents

Tert-Butyldimethylsilyl Amine (TBDMS-NH2): A Mild and Green Reagent for the Protection of Benzyl Alcohols, Phenols, and Carboxylic Acids under Solvent-Free Conditions

Herein, we present the use of the tert-butyldimethylsilyl amine (TBDMS-NH2) as a silylating reagent for phenols, benzyl alcohols, and carboxylic acids. Unlike other silyl protection reactions, this reported process with TBDMS-NH2 does not involve the form

Triphenylphosphine-catalyzed dehydrogenative coupling reaction of carboxylic acids with silanes - A convenient method for the preparation of silyl esters

Triphenylphosphine has been found to be an efficient catalyst for the dehydrosilylation of carboxylic acids with silanes. In the presence of 4 mol % of triphenylphosphine (PPh3), dehydrosilylation reactions in DMF afforded the corresponding silyl esters at 120 °C in good yield.

Effective silylation of carboxylic acids under solvent-free conditions with tert-butyldimethylsilyl chloride (TBDMSCL) and triisopropylsilyl chloride (TIPSCL)

Varions types of carboxylic acids can be converted effectively to their corresponding TBDMS and TIPS esters using TBDMSCI and TIPSCI in the presence of imidazole under solvent-free conditions. The advantage of this modified method in comparison with that reported by Corey is the elimination of DMF, which eliminates aqueous work-up. The method is not a time-consuming process and the reactions proceed spontaneously. By this method, absolute chemoselectivity for the protection of carboxylic acid functions in the presence of 2°, 3° hydroxyl groups are observed.