75755-45-2

Upstream product

• 55577-65-6 2,N-dimethyl-N-phenylpropanamide 
• 100-61-8 N-methylaniline 

Downstream Products

• 17626-86-7 2-isopropyl-benzothiazole 
• 75755-42-9 3-Aethoxy-5,5-dimethyl-2-(N-methylanilino)-1-pyrrolin-4,4-dicarbonitril 
• 75755-40-7 2,2-dimethyl-3-(N-methyl-N-phenylamino)-2H-azirine 
• 58933-81-6 1-(1-chloro-2-methylprop-1-enyl)-N-methyl-N-phenylamine 

Relevant academic research and scientific papers

Preference of cis-Thioamide Structure in N-Thioacyl- N-methylanilines

The thioamide group represents a highly attractive isostere of the amide bond. We report a combined structural and computational study on cis-thioamide conformation of N-thioacyl-N-methylanilines. Amide to thioamide replacement in a class of anilides that

An efficient synthesis of benzothiazole using tetrabromomethane as a halogen bond donor catalyst

An efficient and mild protocol has been developed for the synthesis of 2-substituted benzothiazole under solvent- and metal-free conditions using CBr4 as the catalyst. This process involves the activation of a thioamide through halogen bond formation between the sulphur atom of the thioamide and bromine atom of the CBr4 molecule. The presence of halogen-bonding interaction between N-methylthioamides and tetrabromomethane has been demonstrated with several control experiments, spectroscopic analysis and density functional theory (DFT). This methodology has a wide substrate scope for the synthesis of both 2-alkyl and 2-aryl substituted benzothiazoles.

2,4-Bis(4-methylphenylthio)-1,3,2λ5,4λ5-dithiadiphosphetane-2,4-dithione: A New Reagent for Thiation of N,N-Disubstituted Amides

As a new reagent for the thiation of amides, the easily accessible 2,4-bis(4-methylphenylthio)-1,3,2λ5,4λ5-dithiadiphosphetane-2,4-dithione (9) shows a remarkable selectivity.This selectivity - the preferred thiation of N,N-disubstituted amides - is complementary to the one of the well known Lawesson reagent.Thiation of diamides of type 2 with 9 leads via cyclization of the corresponding dithiodiamides directly to 1,3-thiazole-5(4H)-thiones 1.

Photochemically Induced Reactions of 3-Amino-2H-azirines

Irradiation of 3-(N-methylanilino)-2H-azirines with a mercury low pressure lamp induces the cleavage of the C(2), C(3)-ring bond thus affording nitriliomethanide dipols, substituted by an amino group at C(1).Depending on the substitution pattern at C(3),